The DURABILITY II study provides outcomes in 220 patients treated with nitinol self-expanding stent placement for femoro-popliteal disease out to three years. In this core lab adjudicated study, the EverFlex™ (Covidien, Plymouth, MN) self-expanding stents had a low stent fracture rate (0.9%). The study demonstrated a freedom from clinically driven target lesion revascularization (TLR) of nearly 70% at 3 years. Based on this study, primary angioplasty and stenting of these lesions is a reasonable strategy though results are better with lesions less than 8 cm compared to those greater than 8 cm. Further research is need comparing this strategy to use of drug-coated stents and that of atherectomy with drug eluting balloons and with longer term follow-up.
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http://dx.doi.org/10.1002/ccd.26067 | DOI Listing |
Parasit Vectors
January 2025
Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, UK.
Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. They pose a significant risk to public health with over 200 million cases of malaria per annum and approximately 4 billion people at risk of arthropod-borne viruses (arboviruses). Mosquito populations are geographically expanding into temperate regions and their distribution is predicted to continue increasing.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand.
Carcinoembryonic antigen (CEA) and C-reactive protein (CRP) are biomacromolecules known as cancer and inflammatory markers. Thus, they play a crucial role in early cancer diagnosis, post-treatment recurrence detection, and tumor risk assessment. This paper describes the development of an ultrasensitive and selective imprinted paper-based analytical device (PAD) as impedance sensor for determination of CEA and CRP in serum samples for point-of-care testing (POCT).
View Article and Find Full Text PDFEvid Based Dent
January 2025
Eastman Dental Institute, London, UK.
Design: A retrospective cohort study assessing the mid-to-long-term outcomes and risk factors affecting the prosthetic success and survival of implant-supported cross-arch fixed dental prostheses (IFCDPs) with monolithic zirconia frameworks.
Cohort Selection: Forty-seven patients received a total of 51 cross-arch prostheses (27 maxillary and 24 mandibular prostheses), supported by 302 implants. Comprehensive clinical and radiographic records were available over a follow-up period ranging from 5 to 13 years.
Sci Rep
January 2025
Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
This study aimed to compare the bonding efficacy three bioactive self-adhesive restorative systems to dentin. A total of 80 permanent human molars were utilized in this study. The occlusal enamel was removed to exposed mid-coronal dentin; 40 molars were used for microshear bond strength testing, while the remaining molars were used for micromorphological analysis of restoration/dentin interface.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Textile and Clothing Engineering, Soochow University, 199 Ren-ai Road, Suzhou 215123, China; Jiangsu Engineering Research Center of Textile Dyeing and Printing for Energy Conservation, Discharge Reduction and Cleaner Production (ERC), 215123, China; State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, China. Electronic address:
Conductive organohydrogel fibers based on sodium alginate (SA) exhibit remarkable flexibility and electrical conductivity, making them ideal candidates for conformal skin adhesion and real-time monitoring of human activity signals. However, traditional conductive hydrogels often suffer from issues such as uneven distribution of conductive fillers, and achieving the integration of high mechanical strength, stretchability, and transparency using environmentally friendly methods remains a significant challenge. In this study, a novel and sustainable strategy was developed to fabricate dual-network organohydrogel fibers using sodium alginate as the primary material.
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