The purpose of this single-surgeon randomized study was to determine if functional recovery during the early postoperative period differs between the direct anterior (DAA) and posterior approaches (PA). An a priori power analysis indicated that 26 patients per group were needed, and 6-week follow-up data were available for 51 THAs to date. Hospitals stays were significantly shorter for the DAA group (1.4 vs. 2.0 days, P=0.01), and the change in Pain Scores was significantly greater for the DAA group (P=0.04). The DAA group also discontinued use of an assistive ambulatory device at an earlier time (33.0 vs. 43.1 days, P=0.03). Despite these differences, no other subjective or objective functional measures differed between the 2 groups at the 6-week follow-up.
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http://dx.doi.org/10.1016/j.arth.2014.12.038 | DOI Listing |
J Viral Hepat
February 2025
Clinica Universidad de Navarra, Pamplona, Spain.
Direct-acting antiviral (DAA) therapy is associated with a significant reduction in hepatocellular carcinoma (HCC) incidence among patients with cirrhosis, but data are conflicting about the risk of recurrence following DAA therapy. DAA-PASS was a prospective, pragmatic, observational study designed to estimate the risk of HCC recurrence associated with DAA therapy exposure during routine clinical care. Eligible patients were DAA treatment naive with Barcelona Clinic Liver Cancer (BCLC) stage A.
View Article and Find Full Text PDFFish Shellfish Immunol
January 2025
Vet Products Research & Innovation Center Co., Ltd, 141 Moo9, Thailand Science Park, Innovation Clusters (INC2) Tower D 11th floor, Room No. INCD1108-INCD1111 Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand.
Recently, microsporidiosis caused by a microsporidian [Ecytonucleospora (Enterocytozoon) hepatopenaei, EHP] has been found to seriously impact the global shrimp industry. The aim of this study was to evaluate the therapeutic effects of fumaric acid (FA) in EHP-infected Pacific white shrimp (Penaeus vannamei). In the first 2 groups, non-EHP-infected shrimp were fed FA-supplemented (10 g/kg diet) or normal feed (CM+ and CM-, respectively).
View Article and Find Full Text PDFBackground: Sequential soft tissue releases are utilized in direct anterior approach (DAA) total hip arthroplasty (THA) as incomplete femoral exposure may lead to complications. This study identifies patient-specific parameters associated with soft tissue releases required for femoral exposure.
Methods: A retrospective review was conducted on 133 patients (150 hips) who underwent primary THA via DAA with a single surgeon.
Clin Infect Dis
January 2025
Veteran Affairs Portland Health Care System, Portland, OR, USA.
Background: Chronic hepatitis C virus (HCV) infection affects >1% of the U.S. population, higher among U.
View Article and Find Full Text PDFViruses
December 2024
World Health Organization, 1202 Geneva, Switzerland.
Setting up a global SARS-CoV-2 surveillance system requires an understanding of how virus isolation and propagation practices, use of animal or human sera, and different neutralisation assay platforms influence assessment of SARS-CoV-2 antigenicity. In this study, with the contribution of 15 independent laboratories across all WHO regions, we carried out a controlled analysis of neutralisation assay platforms using the first WHO International Standard for antibodies to SARS-CoV-2 variants of concern (source: NIBSC). Live virus isolates (source: WHO BioHub or individual labs) or spike plasmids (individual labs) for pseudovirus production were used to perform neutralisation assays using the same serum panels.
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