Objective: To discuss the occurrence of thrombosis in portal system of patients with cirrhotic portal hypertension after devascularization and the methods for treatment and prevention.
Methods: The clinical data of 113 patients with cirrhotic portal hypertension after the devascularization were collected and analyzed retrospectively, and the occurrence time, parts as well as the treatment and prevention methods were discussed.
Results: Among the 113 patients, 33 of them were found with thrombosis in their portal system, and the occurrence rate was 29.2%. The occurrence time of thrombosis was 2-15 days post-devascularization, and the median time was 6 days post-operation. Among the 33 cases with thrombosis, there were 19 cases of splenic vein thrombosis, 10 cases of portal thrombosis, and 4 cases of both of them. After the thrombolytic therapy, the thrombosises in 30 cases disappeared.
Conclusions: Most of the thrombosises in portal system happen in splenic vein post-devascularization. Avoiding clamping the trunk of splenic vein in the operation and taking thrombolytic therapy at the early stage after the operation can effectively prevent the occurrence of thrombosis.
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Medicina (Kaunas)
November 2024
Imperial College London and Healthcare NHS Trust, London SW 2AZ, UK.
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Medical Clinic 1, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
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Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais - UFMG, Belo Horizonte, Minas Gerais, Brazil; National Institute of Science and Technology in NanoBiopharmaceutics (INCT-Nanobiofar), Belo Horizonte, Minas Gerais, Brazil.
Cardiovascular involvement in Leishmania sp. infections still requires further elucidation, with cutaneous and organic changes being more frequently observed. The aim of this study was to conduct a systematic review of cardiovascular involvement in dogs with canine visceral leishmaniasis, considering a publication span of over 80 years.
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