Protection zoning of karst springs and wells used for water supply is a key aspect in many countries, calling for specific methodologies adapted to the particular characteristics of karst media. This work presents a new approach, in view of the present state of the art and based on experiences with contamination vulnerability mapping at the pilot site of the Villanueva del Rosario karst system (southern Spain). Source (intrinsic) vulnerability maps were prepared and compared using three European procedures for karst aquifers. The vulnerability maps were then tested using dye tracers. The COP+K method and Slovene Approach appear to provide reliable results in terms of intrinsic vulnerability mapping. Nevertheless, all the methods have a margin of error. The COP+K map is adopted as the baseline to delineate the protection zones, through the conversion from vulnerability classes to degrees of protection.
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http://dx.doi.org/10.1016/j.scitotenv.2015.05.029 | DOI Listing |
Zoology (Jena)
January 2025
Laboratory of Ecology and Environmental Management, Science and Technology Advanced Institute, Van Lang University, Ho Chi Minh City, Vietnam; Faculty of Applied Technology, School of Technology, Van Lang University, Ho Chi Minh City, Vietnam. Electronic address:
Floods, which occur when the amount of precipitation surpasses the capacity of an area to drain it adequately, have detrimental consequences on the survival and future generations of fishes. However, few works have reported the prediction of this natural phenomenon in a relation to certain fish species, especially in fast-flowing rivers. In the specific context of the northern mountainous provinces of Vietnam, where the Spinibarbus sp.
View Article and Find Full Text PDFRedox Biol
January 2025
Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute/National Institutes of Health, 37 Convent Drive, Bethesda, MD, 20892, USA. Electronic address:
Metabolic pathways fuel tumor progression and resistance to stress conditions including chemotherapeutic drugs, such as DNA damage response (DDR) inhibitors. Yet, significant gaps persist in how metabolic pathways confer resistance to DDR inhibition in cancer cells. Here, we employed a metabolism-focused CRISPR knockout screen and identified genetic vulnerabilities to DDR inhibitors.
View Article and Find Full Text PDFIntroduction: The Tanzania HIV Impact Survey (THIS) 2022-2023 showed that HIV prevalence among the general population stabilises but varies geographically across the country. Despite this, disproportionate burdens of HIV continue among specific subpopulations, such as fishermen. Fishermen are particularly vulnerable to HIV infection and have a low uptake of HIV prevention and treatment services.
View Article and Find Full Text PDFBMC Public Health
January 2025
Research Department of Primary Care & Population Health, University College London, UCL Medical School (Royal Free Campus), Upper Third Floor, Rowland Hill Street, London, NW3 2PF, UK.
Background: Advances in digital healthcare and health information provide benefits to the public. However, lack of digital skills together with access, confidence, trust and motivation issues present seemingly insurmountable barriers for many. Such digital health exclusion exacerbates existing health inequalities experienced by older people, people with less income, less education or who don't have English as a first language.
View Article and Find Full Text PDFColorectal cancer is the second leading cause of cancer-related deaths worldwide, and its development typically involves complex metabolic reprogramming. By mapping the spatial distributions of metabolites and -glycans in heterogeneous colorectal cancer tissues, we can elucidate cancer-associated metabolic and -glycan changes. Herein, we combine mass spectrometry imaging-based metabolomics and -glycomics to characterize the spatially resolved reprogramming of metabolites and -glycans in colorectal cancer tissues.
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