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Management of metastatic colorectal cancer: consensus in the Gulf Cooperation Council countries.
Ther Adv Med Oncol
January 2025
Tawam Hospital, po box 15254, Al Ain, United Arab Emirates.
Colorectal cancer (CRC) represents a major public health challenge globally, particularly in the Gulf Cooperation Council (GCC) countries, where it is identified as the second most prevalent form of cancer. Despite advancements in management strategies, tailored guidelines specific to the Gulf region are lacking. This paper presents consensus recommendations developed by a panel of experts from the GCC countries to address this gap.
View Article and Find Full Text PDFIntroduction Urinary tract infections (UTIs) are one of the most common bacterial infections encountered in community and healthcare settings. Increasing antimicrobial resistance patterns worldwide have limited the treatment options available. Overuse of carbapenems which were considered as the last resort for multi-drug resistant UTIs over the past decade has led to the emergence of carbapenem-resistant Enterobacterales (CRE).
View Article and Find Full Text PDFThe substance use profiles of adults who sought mental health and addiction services through a centralized intake process in Nova Scotia (2020-2021).
Front Psychiatry
December 2024
Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Background: Despite the increasing substance use in Canada, our understanding of how substance use varies based on the intersections of gender, ethnicity/race, and income sources among preclinical populations remains limited. Thus, this study aimed to investigate, among clients of mental health and addiction (MHA) intake in Nova Scotia: 1) the prevalence of substance use by gender, ethnicity, and income source; 2) the routes of substance administration; 3) factors associated with substance use. Understanding how gender, ethnicity, and income sources intersect to influence substance use patterns is essential for designing prevention and treatment strategies tailored to an individual's unique needs.
View Article and Find Full Text PDFThe Virulence Gene and Drug Resistance Analysis of Shiga Toxin-Producing from Diarrhea Calves in Xinjiang, China.
Foodborne Pathog Dis
January 2025
College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi, China.
This investigation aimed to examine the virulence genes and antimicrobial resistance profiles of Shiga toxin-producing (STEC) strains found in diarrheal calves in Xinjiang between 2016 and 2022. A total of 800 samples, including 232 fecal and 568 rectal swabs from calves under 2 months old with diarrhea, were analyzed for Shiga toxin (Stx)-encoding genes using polymerase chain reaction. The study characterized the isolates based on their subtypes, virulence genes, O serogroups, phylogenetic groups, hemolytic phenotypes, antibiotic resistance, and resistance genes.
View Article and Find Full Text PDFClinical profile, staging and oncological treatment of ten leading cancer types between young vs older patients from 2000 to 2019 in Brazil.
Cancer Epidemiol
January 2025
Clinical Epidemiology Program, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil.
Introduction: Cancer has become a public health problem worldwide, affecting individuals of different age groups, including children, young adults and older patients.
Objective: To determine the clinical profile, staging and standard of oncological treatment of the 10 most frequent primary sites of cancer in young patients (< 60 years) vs older patients (≥ 60 years old) diagnosed between 2000 and 2019 in Brazil.
Materials And Methods: This cross-sectional study used data from the secondary database of the Hospital Cancer Registry, available on the web www.
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