Self-efficacy is important to functioning in schizophrenia. The exact pathway is less clear, possibly because most studies used composite rather than domain-specific self-efficacy scores. We examined if a specific measure of social self-efficacy is more important to a social (from negative symptoms to social functional capacity) compared to a non-social (from neurocognition to non-social functional capacity) path to functioning. Associations between social self-efficacy and negative symptoms, neurocognition and social and non-social functional capacity were examined in a cross-sectional study of schizophrenia (n=51). Two models were investigated using bootstrapping methods to test for mediation. In Model I, social self-efficacy was entered as a mediator; in Model II as a predictor. Social self-efficacy was unrelated to neurocognition and non-social functional capacity. Associations with negative symptoms and social functional capacity were significant. Negative symptoms were found to mediate between social self-efficacy and social functional capacity. Support was found for a social path to functioning in schizophrenia, going from social self-efficacy through negative symptoms to social functional capacity. Our results are consistent with the idea that negative symptoms can develop as a reaction to self-defeatist beliefs. Future studies should use domain-specific self-efficacy to further understand predictors of functioning in schizophrenia.
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http://dx.doi.org/10.1016/j.psychres.2015.05.019 | DOI Listing |
Vet Res Commun
January 2025
Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Ruta N 36 Km 601, Río Cuarto City, 5800, Córdoba, Argentina.
Post-weaning diarrhea (PWD) is a major concern for pig producers, as stress and early weaning increase susceptibility to enteropathogens like enterotoxigenic Escherichia coli (ETEC) and Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium).
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, , 11829, Cairo, Egypt.
Globally, the incidence and death rates associated with cancer persist in rising, despite considerable advancements in cancer therapy. Although some malignancies are manageable by a mix of chemotherapy, surgery, radiation, and targeted therapy, most malignant tumors either exhibit poor responsiveness to early identification or endure post-treatment survival. The prognosis for prostate cancer (PCa) is unfavorable since it is a perilous and lethal malignancy.
View Article and Find Full Text PDFExp Brain Res
January 2025
School of Rehabilitation Sciences, Université Laval, Quebec, Canada.
Navigating public environments requires adjustments to one's walking patterns to avoid stationary and moving obstacles. It is known that physical inactivity induces alterations in motor capacities, but the impact of inactivity on anticipatory locomotor adjustments (ALA) has not been studied. The purpose of the present exploratory study was to compare ALAs and related muscle co-contraction during a pedestrian circumvention task between active (AA) and inactive young adults (IA).
View Article and Find Full Text PDFJ Mol Model
January 2025
Escuela Superior de Física y Matemáticas, IPN S/N, Edificio 9 de la Unidad Profesional "Adolfo López Mateos", Col. Lindavista, Alc. Gustavo A. Madero, 07738, Mexico City, Mexico.
Context: "Nanostructure of graphene-reinforced with polymethyl methacrylate" (PMMA-G), and vice versa, is investigated using its molecular structure, in the present work. The PMMA-G nanostructure was constructed by bonding PMMA with graphene nanosheet in a sense to get three different configurations. Each configuration consisted of polymeric structures with three degrees of polymerization (such as monomers, dimers, and trimers polymers, respectively).
View Article and Find Full Text PDFCancer Chemother Pharmacol
January 2025
Markey Cancer Center, University of Kentucky, Lexington, KY, USA.
Purpose: Patients with partial or complete DPD deficiency have decreased capacity to degrade fluorouracil and are at risk of developing toxicity, which can be even life-threatening.
Case: A 43-year-old man with moderately differentiated rectal adenocarcinoma on capecitabine presented to the emergency department with complaints of nausea, vomiting, diarrhea, weakness, and lower abdominal pain for several days. Laboratory findings include grade 4 neutropenia (ANC 10) and thrombocytopenia (platelets 36,000).
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