Background: Recently, artificial neural networks (ANNs) have been widely applied in science, engineering, and medicine. In the present study, we evaluated the ability of artificial neural networks to be used as a computer program and assistant tool in the diagnosis of obstructive sleep apnea (OSA). Our hypothesis was that ANNs could use clinical information to precisely predict cases of OSA.
Method: The study population in this clinical trial consisted of 201 patients with suspected OSA (140 with a positive diagnosis of OSA and 61 with a negative diagnosis of OSA). The artificial neural network was trained by assessing five clinical variables from 201 patients; efficiency was then estimated in this group of 201 patients. The patients were classified using a five-element input vector. ANN classifiers were assessed with the multilayer perceptron (MLP) networks.
Results: Use of the MLP classifiers resulted in a diagnostic accuracy of 86.6 %, which in clinical practice is high enough to reduce the number of patients evaluated by polysomnography (PSG), an expensive and limited diagnostic resource.
Conclusions: By establishing a pattern that allows the recognition of OSA, ANNs can be used to identify patients requiring PSG.
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http://dx.doi.org/10.1007/s11325-015-1218-7 | DOI Listing |
Environ Sci Technol
January 2025
Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Qingdao 266237, P. R. China.
Membrane distillation (MD) efficiently desalinizes and treats high-salinity water as well as addresses the challenges in handling concentrated brines and wastewater. However, silica scaling impeded the effectiveness of MD for treating hypersaline water and wastewater. Herein, the effects of humic acid (HA) on silica scaling behavior during MD are systematically investigated.
View Article and Find Full Text PDFiScience
January 2025
Department of Artificial Intelligence, Hanyang University, Seoul 04763, South Korea.
We present a Fourier neural operator (FNO)-based surrogate solver for the efficient optimization of wavefronts in tunable metasurface controls. Existing methods, including the Gerchberg-Saxton algorithm and the adjoint optimization, are often computationally demanding due to their iterative processes, which require numerical simulations at each step. Our surrogate solver overcomes this limitation by providing highly accurate gradient estimations with respect to changes in tunable meta-atoms without the need for direct simulations.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology&Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Key Laboratory of Intelligent Diagnosis, Treatment and Prevention of Blinding Eye Diseases, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Retinal diseases can severely impair vision and even lead to blindness, posing significant threats to both physical and mental health. Physical retinal regenerative therapies are poised to revolutionize the treatment of various disorders associated with blindness. However, these therapies must overcome the challenges posed by the protective inner and outer blood‒retinal barriers.
View Article and Find Full Text PDFKnee Surg Relat Res
January 2025
Bioengineering Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Background: Unplanned readmission, a measure of surgical quality, occurs after 4.8% of primary total knee arthroplasties (TKA). Although the prediction of individualized readmission risk may inform appropriate preoperative interventions, current predictive models, such as the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) surgical risk calculator (SRC), have limited utility.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China.
Background: MicroRNAs (miRNAs) are pivotal in the initiation and progression of complex human diseases and have been identified as targets for small molecule (SM) drugs. However, the expensive and time-intensive characteristics of conventional experimental techniques for identifying SM-miRNA associations highlight the necessity for efficient computational methodologies in this field.
Results: In this study, we proposed a deep learning method called Multi-source Data Fusion and Graph Neural Networks for Small Molecule-MiRNA Association (MDFGNN-SMMA) to predict potential SM-miRNA associations.
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