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Serum Inflammatory Markers and Integrity of the Superior Longitudinal Fasciculus and the Inferior Longitudinal Fasciculus in Schizophrenia, from Prodromal Stages to Chronic Psychosis-A Cross-Sectional Study.
J Clin Med
January 2023
Department of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.
Chronic subclinical inflammation is believed to be an important factor in the pathogenesis of schizophrenia. Meta-analyses confirm the presence of increased levels of peripheral inflammatory markers (IM) in schizophrenia and its prodromal stages. Peripheral cytokines may affect the brain microstructure through chronic activation of microglia.
View Article and Find Full Text PDFVisual pathway function in untreated individuals with major depression.
Adv Clin Exp Med
January 2023
Department of Psychiatry, Pomeranian Medical University, Szczecin, Poland.
Background: Major depression (MD) is the one of the most debilitating diseases, affecting millions of people all around the world.
Objectives: To establish visual pathway function in untreated individuals with MD.
Material And Methods: In 29 untreated, newly diagnosed, ophthalmologically asymptomatic individuals (58 eyes) with MD (mean age: 47.
Serum Inflammatory Markers and Their Associations with the Integrity of the Cingulum Bundle in Schizophrenia, from Prodromal Stages to Chronic Psychosis.
J Clin Med
October 2022
Department of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.
Article Synopsis
- Peripheral cytokines can impact the brain by activating microglia, which may lead to damage in the cingulum bundle (CB) white matter.
- The study examined the connection between inflammatory markers and CB integrity across different states of mental health, using diffusion tensor imaging to measure integrity.
- While some differences in inflammatory markers (like IL-6 and IFN-γ) were noted, no strong link was confirmed between these markers and CB integrity after correcting for multiple comparisons, suggesting the need for further research.
Odors identification differences in deficit and nondeficit schizophrenia.
Pharmacol Rep
April 2016
Department of Psychiatry, Pomeranian Medical University, Szczecin, Poland. Electronic address:
Background: There is evidence that deficit schizophrenia (DS) is associated with neuroanatomical changes in structures including those involved in olfaction. Olfactory dysfunction, which includes impaired odor identification, is found in patients with schizophrenia and their family members.
Methods: 82 patients with DS and 72 patients with NDS (nondeficit schizophrenia), somatically healthy and without acute psychotic symptoms undertook a smell identification test using the 16-item Sniffin' Sticks ID test.
Correction: Samochowiec, A., et al. Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology. Int. J. Environ. Res. Public Health 2015, 12, 3317-3326.
Int J Environ Res Public Health
June 2015
Department of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland.
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