Oxidative conversion of δ-sultones to γ-lactones.

Tetrahedron Lett

University of North Dakota, 151 Cornell St. Stop 9024, Grand Forks, ND 58202, USA.

Published: April 2015

Delta-sultones, prepared by C-H insertion, can be oxidatively converted to gamma-lactones by treatment with t-BuOK/t-BuOOH. An intermediate in the synthesis of (-)-eburnamonin was prepared using this approach.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465188PMC
http://dx.doi.org/10.1016/j.tetlet.2015.03.038DOI Listing

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