The objective of this study was to develop an alternative strategy for the control of Spodoptera litura larvae by using botanical insecticides. Rhizomes of Alpinia galanga were extracted with hexane, dichloromethane, ethyl acetate and methanol, respectively. Each crude extract was examined for toxicity against the second instars of S. litura according to a topical application method. The dichloromethane extract was found to show the highest toxicity of all the extracts, with LD50 = 3177 and 2099 ppm at 24 and 48 h post-treatment, respectively.
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Plant Dis
January 2025
Hainan University School of Tropical Agriculture and Forestry, Haikou, Hainan, China;
Katsumada galangal seed ( K. Schum) is an important member of the Zingiberaceae family, with both medicinal value and culinary applications (Park et al. 2020).
View Article and Find Full Text PDFSci Rep
January 2025
College of Ecology and Environment, Hainan University, Haikou, 570228, China.
Agroforestry systems are known to enhance soil health and climate resilience, but their impact on greenhouse gas (GHG) emissions in rubber-based agroforestry systems across diverse configurations is not fully understood. Here, six representative rubber-based agroforestry systems (encompassing rubber trees intercropped with arboreal, shrub, and herbaceous species) were selected based on a preliminary investigation, including Hevea brasiliensis intercropping with Alpinia oxyphylla (AOM), Alpinia katsumadai (AKH), Coffea arabica (CAA), Theobroma cacao (TCA), Cinnamomum cassia (CCA), and Pandanus amaryllifolius (PAR), and a rubber monoculture as control (RM). Soil physicochemical properties, enzyme activities, and GHG emission characteristics were determined at 0-20 cm soil depth.
View Article and Find Full Text PDFAnal Methods
January 2025
Pharmacognosy Division, CSIR-National Botanical Research Institute, Lucknow, UP, 226001, India.
This work deals with the development of a greener RP-HPLC method and chemical pattern recognition for the identification of L. collected from different natural sources and samples traded as '' in Indian herbal drug markets. The simultaneous quantification of α- and β-asarone was performed using 0.
View Article and Find Full Text PDFChemMedChem
January 2025
University of Michigan Michigan Medicine, Internal Medicine, 2800 Plymouth Rd, NCRC 26-220S, 48109, Ann Arbor, UNITED STATES OF AMERICA.
A key molecular dysfunction in heart failure is the reduced activity of the cardiac sarcoplasmic reticulum Ca2+-ATPase (SERCA2a) in cardiac muscle cells. Reactivating SERCA2a improves cardiac function in heart failure models, making it a validated target and an attractive therapeutic approach for heart failure therapy. However, finding small-molecule SERCA2a activators is challenging.
View Article and Find Full Text PDFMol Med
January 2025
School of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Glioblastoma multiforme (GBM) represents a primary brain tumor that is widely prevalent, and clinical drugs available for its treatment exhibit varying degrees of resistance. Nootkatone (NKT) is a functional sesquiterpene sourced from traditional Chinese medicine --Alpinia Oxyphylla Miq and has been reported to have a diverse range of pharmacological properties. However, it remains unknown whether there are effects of NKT on GBM.
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