[Study on Megastigmane Glycosides and Lignan Constituents from Leaves of Psidium littorale].

Objective: To study the chemical constituents of the leaves of Psidium littorale.

Methods: The constituents were isolated with silica gel column chromatography and the structures of these compounds were elucidated on the basis of spectral analysis.

Results: Four megastigmane glycosides and three lignans were isolated and their structures were identified as Bridelionoside B(1), Euodinoside E(2), (3S,5R,6R,7E,9S)-Megastignan-7-ene-3,5,6,9-tetrol 9-O-β-D-glucopyranoside (3), Bridelionoside C(4), (--)-Isolaricires-inol 3-α-O-β-D-glucopyranoside (5), (--)-5'-methoxy-Isolariciresinol 3-α-O-β-D-glucopyranoside (6) and dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside(7).

Conclusion: Compounds 1-7 are isolated from this plant for the first time. The results have provided the scientific basis for further exploitation of Psidium littoratle.