It is shown on the prototrophic strain Streptomyces kanamyceticus that relative biological activity of neutrons is higher than that of gamma rays and depends on the bundle energy. The mutagenic efficiency of superfast neutrons is 2-3 times as high as the effect of neutrons with the energy of 1.4-1.6 MeV. The antibiotic production trait in the obtained variants of S. kanamyceticus is established to be unstable. Variants obtained under the effect of superfast neutrons are more stable. The promising strains are obtained for the further breeding.

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