Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/SLA.0000000000001272 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hepatic artery restriction operation combined with ALPPS (HARO-ALPPS), a novel ALPPS procedure for the treatment of hepatocellular carcinoma with severe fibrosis: retrospective clinical cohort study.
Int J Surg
September 2024
Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Background: Associating liver partition with portal vein ligation for staged liver resection (ALPPS) has been used in the treatment of patients with advanced or massive liver cancer without sufficient future liver remnant, but concerns remain regarding tumor outcomes and surgical safety. This study aims to evaluate the efficacy and safety of a new procedure, hepatic artery restriction operation combined with ALPPS (HARO-ALPPS), in the treatment of hepatocellular carcinoma (HCC) patients especially with severe fibrosis.
Methods: This retrospective study analyzed 8 patients who underwent HARO-ALPPS for HCC and compared their outcomes with 64 patients who underwent conventional ALPPS.
Is ALPPS still appropriate for large or locally advanced hepatocellular carcinoma in an era of targeted agents and immunotherapy?
Updates Surg
June 2024
Hepatic Surgery Center, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, China.
Article Synopsis
- This study compares the effectiveness and safety of a combination therapy (dTACE-PVE-TKI-ICI) against a surgical method (ALPPS) for treating large or locally advanced hepatocellular carcinoma (HCC).
- Results show that the quadruple therapy led to complete tumor necrosis in some patients, with a significant increase in future remnant liver volume compared to ALPPS.
- The findings suggest that the combination therapy not only improved tumor resectability with manageable complications but also highlighted the need to reconsider surgical approaches in light of new molecular and immune treatments.
Robotic ALPPS for primary and metastatic liver tumours: short-term outcomes versus open approach.
Updates Surg
April 2024
Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, 41124, Modena, Italy.
Article Synopsis
- The study focuses on comparing the short-term outcomes of a robotic approach versus the traditional open method for a surgical procedure called ALPPS, used for patients with liver conditions that make surgery challenging.
- By analyzing data from 23 patients treated at a University hospital over several years, researchers aimed to evaluate the safety and effectiveness of the robotic technique.
- Results indicated that the robotic method was associated with fewer complications, shorter hospital stays, and a lower risk of mortality compared to the open approach, highlighting its potential benefits in surgical practice.
Efficacy and perioperative safety of different future liver remnant modulation techniques: a systematic review and network meta-analysis.
HPB (Oxford)
April 2024
Department of Surgery, Poliambulanza Foundation Hospital, Brescia, Italy; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom. Electronic address:
Background: In daily clinical practice, different future liver remnant (FLR) modulation techniques are increasingly used to allow a liver resection in patients with insufficient FLR volume. This systematic review and network meta-analysis aims to compare the efficacy and perioperative safety of portal vein ligation (PVL), portal vein embolization (PVE), liver venous deprivation (LVD) and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS).
Methods: A literature search for studies comparing liver resections following different FLR modulation techniques was performed in MEDLINE, Embase and Cochrane Central, and pairwise and network meta-analyses were conducted.
Comparison of clinical efficacy between LAPS and ALPPS in the treatment of hepatitis B virus-related hepatocellular carcinoma.
Gastroenterol Rep (Oxf)
October 2023
Centre of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, P. R. China.
Background: Insufficient post-operative future liver remnant (FLR) limits the feasibility of hepatectomy for patients. Staged hepatectomy is an effective surgical approach that can improve the resection rate of hepatocellular carcinoma (HCC). This study aimed to compare the safety and efficacy of laparoscopic microwave ablation and portal vein ligation for staged hepatectomy (LAPS) and classical associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in the treatment of hepatitis B virus (HBV)-related HCC.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!