An efficient and straight forward procedure for the syntheses of bicyclic isoxazole/isoxazoline derivatives from the corresponding dimethyl-2-(2-nitro-1-aryl/alkyl)-2-(prop-2-yn-1yl)malonates or dimethyl 2-allyl-2-(2-nitro-1-aryl/alkyl ethyl)malonate is described. High yields and simple operations are important features of this methodology.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272556 | PMC |
| http://dx.doi.org/10.3390/molecules200610910 | DOI Listing |
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