AI Article Synopsis
- The study evaluated the effectiveness of different materials for vocal cord medialization in dogs, including lyophilized glutaraldehyde-preserved bovine pericardium (LGPBP), PTFE, PET, and Teflon felt (TF).
- Results showed that LGPBP provided the best surgical handling and led to thinner fibrous capsules around the implants, while TF exhibited issues like extrusion and severe inflammation.
- The findings suggest that LGPBP is a promising option for vocal cord implants due to its biocompatibility, ease of handling, and low inflammatory response compared to synthetic materials.
Article Abstract
This study compared the use of lyophilized glutaraldehyde-preserved bovine pericardium (LGPBP), polytetrafluoroethylene (PTFE), polyethylene terephthalate (PET), and Teflon felt (TF) as implants for vocal cords (VC) medialization and aimed to assess the endoscopic, macroscopic, and microscopic VC changes after medialization in a canine model. In 18 mongrel dogs, the right VC were medialized with LGPBP and the left were implanted as follows: Group I (n = 6): LGPBP and PTFE; Group II (n = 6): LGPBP and PET; Group III (n = 6): LGPBP and TF. Surgical handling of the implants was compared. Three months after surgery, macroscopic and microscopic changes of VC and implants were evaluated. LGPBP offered the best surgical handling (p = 0.005, Kruskal-Wallis). TF implants showed extrusion (p = 0.005, Kruskal-Wallis) and severe inflammation. All VC formed fibrous capsules around the implants; the ones developed by LGPBP implants were thinner (p = 0.001, ANOVA, Tukey). VC implanted with synthetic materials showed eosinophilic infiltration (p = 0.01, Kruskal-Wallis). We concluded that the LGPBP could be used as an implant for VC medialization because it is biocompatible, easy to handle and remove during surgical procedures, and nonabsorbable or extrudable and produces an inflammatory reaction similar to PTFE and PET.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444564 | PMC |
| http://dx.doi.org/10.1155/2015/351862 | DOI Listing |
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Comparison of lyophilized glutaraldehyde-preserved bovine pericardium with different vascular prostheses for use as vocal cords implants: experimental study.
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Medical Direction, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Tlalpan, 14080 Mexico City, DF, Mexico.
Article Synopsis
- The study evaluated the effectiveness of different materials for vocal cord medialization in dogs, including lyophilized glutaraldehyde-preserved bovine pericardium (LGPBP), PTFE, PET, and Teflon felt (TF).
- Results showed that LGPBP provided the best surgical handling and led to thinner fibrous capsules around the implants, while TF exhibited issues like extrusion and severe inflammation.
- The findings suggest that LGPBP is a promising option for vocal cord implants due to its biocompatibility, ease of handling, and low inflammatory response compared to synthetic materials.
[Glutaraldehyde-preserved and lyophilized bovine pericardium as materials for medialization of the vocal folds in an animal model].
Acta Otorrinolaringol Esp
February 2014
Departamento de Cirugía Experimental, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, México, D.F.
Introduction: Glutaraldehyde-preserved bovine pericardium (GBP) and lyophilized GBP (LGBP) have been used successfully in repairing several anatomical defects, but their effectiveness and safety as implants to vocal cords (VC) have not been reported.
Objective: The aim of this study was to evaluate the use of GBP and LGBP as materials for medialization thyroplasty, as well as to assess the endoscopic, macroscopic and microscopic VC changes after medialization in an experimental canine model.
Material And Methods: In 12 healthy mongrel dogs, the right VC were medialized using pericardium and the left with polytetrafluoroethylene (PTFE).
Lyophilized glutaraldehyde-preserved bovine pericardium for experimental atrial septal defect closure.
Eur Cell Mater
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Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas - Surgical Research, Tlalpan, D.F., Mexico.
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- Sixteen dogs underwent surgery to create and close a 3 cm ASD using either LGPBP or Dacron patches, with assessments made over a six-month study period.
- Results showed that LGPBP was successfully integrated into the atrial septum without complications and was effective in reducing the size of the ASD, suggesting it could be a viable alternative to existing patch materials.
Usefulness of bovine pericardium as interpositional graft in the surgical repair of nasal septal perforations (experimental study).
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Department of Experimental Surgery, National Institute of Respiratory Diseases, Mexico City, Mexico.
A 2.5-cm nasal septal perforation was performed in 18 pigs and repaired as follows: group I (n = 6), septal perforation without treatment; group II (n = 6), surgical repair with interpositional graft of glutaraldehyde-preserved bovine pericardium (GPBP); group III (n = 6), surgical repair with interpositional graft of lyophilized GPBP (LGPBP). The animals were evaluated clinically and radiologically (x-ray and CT scan) 2 days before surgery, daily during the first postoperative week, and weekly during the next 6 months.
View Article and Find Full Text PDF[Evaluation of the use of bovine pericardium in non-anatomical lung resections in dogs].
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Departamento de Investigación en Cirugía Experimental, Instituto Nacional de Ciencias Médicas y de la Nutrición Salvador Zubirán.
Unlabelled: In this study we assessed the usefulness, healing, as well as the integration to lung tissue of glutaraldehyde preserved at 0.5% bovine pericardium GPBP and lyophilized (GPBPL), after reinforced resection of lung tissue in dogs by thoracotomy or thoracoscopy.
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