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Management of Lichen Sclerosus and Related Comorbidities at a Tertiary Referral Center: Beyond Topical Steroids.
Dermatol Pract Concept
October 2024
Dermatology Unit, Arcispedale S. Maria Nuova, Reggio Emilia Research Hospital, Azienda Unità Sanitaria Locale IRCCS of Reggio Emilia, Italy.
Introduction: Lichen sclerosus (LS) is a chronic inflammatory dermatosis predominantly affecting the anogenital area, with potential systemic implications.
Objective: Our aim was to elucidate its clinical characteristics and management strategies.
Methods: We conducted a retrospective observational study on adult patients with LS referred to our center between January 2022 and December 2023.
Lichen sclerosus is a chronic, immune-mediated dermatologic disorder primarily affecting the genital skin. Extragenital lichen sclerosus is rare, especially in men. We present a case of ELS in a 23-year-old male with lesions on the left upper extremity that had persisted for seven years.
View Article and Find Full Text PDFClinical presentations and treatment outcomes in extragenital lichen sclerosus: A 34-year multiinstitutional retrospective review.
J Am Acad Dermatol
November 2024
Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:
Morphea and Extragenital Lichen Sclerosus Et Atrophicus Overlap.
Cureus
October 2024
Department of Dermatology, Venereology and Leprology, NKP Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital, Nagpur, IND.
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory condition that affects mainly the genital regions but can occur extragenitally. Extragenital LSA occurs far less often than the genitally located variety and in most cases has been reported in females. A 36-year-old male engineer presented with chronic itchy lesions on the right forearm for more than a year's duration.
View Article and Find Full Text PDFThe relationship between the vaginal and vulvar microbiomes and lichen sclerosus symptoms in post-menopausal women.
Sci Rep
November 2024
Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH, 44106, USA.
Lichen sclerosus is a chronic inflammatory condition of unknown etiology that affects the genital and extragenital skin, which can lead to sexual dysfunction and has been associated with vulvar cancer. The vaginal microbiome has a critical role in gynecologic health, but little is known about the microbiome in lichen sclerosus. This study investigated the vaginal and vulvar microbiomes of 27 post-menopausal women with lichen sclerosus.
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