Background: Herein we report a case of a possible PHACE syndrome without hemangioma of the head but with a large segmental hemangioma of the trunk.
Patients And Methods: A 17-year-old female patient with a medical history of transposition of the great arteries with ventricular septal defect diagnosed at 3 days of life and of coarctation of the aorta diagnosed at 14 years was seen in the dermatology department for a long-standing large rectangular, segmental, atrophic and telangiectasic lesion on her back. The lesion appeared to be a sequel of infantile segmental hemangioma of the trunk, and this was confirmed by history-taking.
Discussion: This case raises the question of a link between infantile segmental hemangioma and underlying cardiovascular disorders. Infantile segmental hemangioma could be a marker of an underlying vascular development defect. The presence of infantile segmental hemangioma, regardless of site, should prompt vascular explorations.
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http://dx.doi.org/10.1016/j.annder.2015.04.164 | DOI Listing |
J Toxicol Pathol
January 2025
Pathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.
We performed morphological and immunohistochemical analyses of erythrocyte-rich vascular proliferative lesions of mesenteric lymph nodes in six male and one female Wistar Hannover rats. These lesions are conventionally diagnosed as hemangiomas due to abundant erythrocytes. Immunostaining was positive for prospero-related homeobox 1 (Prox-1) and/or vascular endothelial growth factor receptor 3 (VEGFR3) in all lesions, suggesting a lymphangitic origin.
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Radiology, Ordos Central Hospital, Ordos, Inner Mongolia, China.
Background: Improvements in the clinical diagnostic use of magnetic resonance imaging (MRI) for the identification of liver disorders have been made possible by gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA). Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) technology is in high demand.
Objectives: The purpose of the study is to segment the liver using an enhanced multi-gradient deep convolution neural network (EMGDCNN) and to identify and categorize a localized liver lesion using a Gd-EOB-DTPA-enhanced MRI.
Case Rep Dent
December 2024
Department of Paediatric Dentistry, Selayang Hospital (Ministry of Health), Batu Caves, Selangor, Malaysia.
Infantile haemangioma (IH) is the most common childhood tumour, often developing in the head and neck region. It may cause disfigurement, functional impairment, or tooth developmental issues when it is present in the oral cavity. We report a case of a 2-month-old boy referred to the paediatric dentistry team with a segmental IH involving the left periorbital, cheek, and hard palate.
View Article and Find Full Text PDFBackground Vertebral hemangiomas (VHs) are benign vascular tumors commonly found within the vertebral bodies of the spine. While most VHs remain asymptomatic and are often discovered incidentally during imaging studies, a subset can become symptomatic, leading to clinical challenges. The optimal treatment approach for symptomatic VHs remains a topic of debate.
View Article and Find Full Text PDFChildren (Basel)
November 2024
Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, 37126 Verona, Italy.
Infantile haemangiomas (IHs) affect 3-10% of infants, 10% of whom need topical or systemic beta-blocker therapy. Propranolol is the first choice for IHs with a high risk of complications. Since more than half of IHs leave a permanent mark, to reduce outcomes, it is essential to start oral propranolol (2-3 mg/kg/day in 2 doses/day) within the 5th month of life (i.
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