The angle between subsequent particle displacement increments is evaluated as a function of the time lag in isotropic turbulence. It is shown that the evolution of this angle contains two well-defined power laws, reflecting the multiscale dynamics of high-Reynolds number turbulence. The probability density function of the directional change is shown to be self-similar and well approximated by an analytically derived model assuming Gaussianity and independence of the velocity and the Lagrangian acceleration.
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http://dx.doi.org/10.1103/PhysRevLett.114.214502 | DOI Listing |
PLoS One
January 2025
Department of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Objectives: To form a unique body weight support-Tai Chi Yunshou (BWS-TCY) training method, apply it to the treatment of upper limb dysfunction after stroke, and provide a new safe and effective treatment method for the clinic.
Methods: A total of 93 subjects were recruited and randomly divided into conventional rehabilitation treatment (CRT) group, BWS-TCY group and traditional robot-assisted training (RAT) group in equal proportions. Subjects in the CRT group received 60 minutes of CRT daily.
Alzheimers Dement
December 2024
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Background: Sex-specific functional-brain changes during memory tasks have been reported along the Alzheimer's disease (AD) continuum. However, mid-life risk factor effects on memory-related neural activation remain less clear in women with increased AD risk. Here we examined brain activations during a modified pattern-separation task and their associations with verbal memory scores in midlife women at risk for AD due to family history.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, San Diego, La Jolla, CA, USA.
Background: Chronic pain is a predictor of cognitive decline and dementia, but whether risk is related to a specific site of pain versus multisite pain is unclear. Multisite chronic pain is theorized to involve hyper-excitability in pain receptors and pain-processing brain regions, possibly caused by neuroinflammation. These factors may increase vulnerability to cognitive decline, particularly in those at elevated risk for Alzheimer's disease.
View Article and Find Full Text PDFBackground: Digital mobility outcomes (DMOs) can be captured using body-worn inertial measurement units (IMUs) in lab-based and real-world environments. DMOs may support differential diagnosis of dementia; for example, Alzheimer's disease (AD) and Lewy body disease (LBD) show unique signatures of gait impairment. Growing evidence suggests that turning impairments are related to cognitive decline.
View Article and Find Full Text PDFBackground: Motoric changes are one of the earlier changes in neurodegenerative diseases such as Alzheimer's disease (AD), but they are often difficult to detect especially in the early stages. In the past, examination of handwriting has been used to investigate motoric changes as a proxy for cognitive impairment. In this study, we explore a wide array of explainable features from the handwriting of patients, obtained using signal processing, and their impact on assessment of AD and Mild cognitive impairment (MCI).
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