AI Article Synopsis

  • A 47-year-old woman experienced worsening abdominal pain, especially in the right upper quadrant, after years of vague discomfort and has a history of peptic ulcer disease.
  • An ultrasound and endoscopy showed normal results, but a specialized HIDA scan revealed a significantly low gallbladder ejection fraction, leading to a diagnosis of biliary dyskinesia.
  • After undergoing laparoscopic cholecystectomy, histopathological analysis found chronic cholecystitis with the rare organism Cystoisospora belli, marking the first reported case in an immunocompetent patient, though it commonly affects immunocompromised individuals.

Article Abstract

A 47-year-old woman presented with a history of vague abdominal pain for several years, which worsened over the past 2 months, with pain more prominent in the right upper quadrant. She also had a history of peptic ulcer disease. The ultrasound scan of right upper quadrant revealed normal gallbladder and oesophagogastroduodenoscopy was unremarkable. A (99m)technetium labelled hepato iminodiacetic acid (HIDA) scan with cholecystokinin provocation demonstrated a decreased gallbladder ejection fraction (EF) of 32%. On this basis, the patient was diagnosed with biliary dyskinesia and underwent an elective laparoscopic cholecystectomy. Histopathological analysis revealed chronic cholecystitis with Cystoisospora belli identified in the gallbladder wall. Cystoisospora has been identified to cause an opportunistic acalculous cholecystitis among immunocompromised hosts, especially those with AIDS. This is the first case report of chronic cholecystitis due to C. belli in an immunocompetent patient.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480090PMC
http://dx.doi.org/10.1136/bcr-2015-209966DOI Listing

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