AI Article Synopsis
- The study investigates the wall characteristics of intracranial vertebral artery hypoplasia (VAH) using advanced imaging techniques to differentiate it from acquired atherosclerotic stenosis.
- A total of 30 patients suspected of VAH were analyzed, leading to the diagnosis of 25 with VAH, of which 16 had atherosclerosis, displaying various characteristics like plaque and wall thickening.
- The research concluded that 3D VISTA imaging is effective in differentiating between atherosclerotic stenosis and VAH, highlighting that VAH patients are more susceptible to atherosclerosis.
Article Abstract
Background: There are few studies for evaluating wall characteristics of intracranial vertebral artery hypoplasia (VAH). The aim of this study was to determine wall characteristics of VAH with three-dimensional volumetric isotropic turbo spin echo acquisition (3D VISTA) images and differentiate between acquired atherosclerotic stenosis and VAH.
Methods: Thirty patients with suspicious VAH by luminograms were retrospectively enrolled between January 2014 and February 2015. The patients were classified as "acquired atherosclerotic stenosis" or "VAH" based on 3D VISTA images. The wall characteristics of VAH were assessed to determine the presence of atherosclerotic lesions, and the patients were classified into two subgroups (VAH with atherosclerosis and VAH with normal wall). Wall characteristics of basilar arteries and vertebral arteries were also assessed. The clinical and wall characteristics were compared between the two groups.
Results: Five of 30 patients with suspicious VAH were finally diagnosed as acquired atherosclerotic stenosis by 3D VISTA images. 25 patients were finally diagnosed as VAH including 16 (64.00%) patients with atherosclerosis and 9 (36.00%) patients with normal wall. In the 16 patients with atherosclerosis, plaque was found in 9 patients, slight wall thickening in 6 patients, and thrombus and wall thickening in 1 patient. Compared with VAH patients with normal wall, VAH patients with atherosclerosis showed atherosclerotic basilar arteries and dominant vertebral arteries more frequently (P = 0.000).
Conclusions: Three-dimensional VISTA images enable differentiation between the acquired atherosclerotic stenosis and VAH. VAH was also prone to atherosclerotic processes.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733753 | PMC |
| http://dx.doi.org/10.4103/0366-6999.158314 | DOI Listing |
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