Acute neonatal parotitis (ANP) is a rare condition, characterised by parotid swelling and other local inflammatory signs. The most common pathogen is Staphylococcus aureus, but other organisms can be implicated. We describe the case of a 13-day-old term newborn, previously healthy, with late-onset group B Streptococcus (GBS) bacteraemia with ANP, who presented with irritability, reduced feeding and tender swelling of the right parotid. Laboratory evaluation showed neutrophilia, elevated C reactive protein and procalcitonin, with normal serum amylase concentration. Ultrasound findings were suggestive of acute parotitis. Empiric antibiotic therapy was immediately started and adjusted when culture results became available. The newborn was discharged after 10 days, with clinical improvement within the first 72 h. Although S. aureus is the most common pathogen implicated in ANP, GBS should be included in the differential diagnosis.
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http://dx.doi.org/10.1136/bcr-2014-209115 | DOI Listing |
Biomed Environ Sci
November 2024
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China;School of Public Health, Binzhon Medical University, Yantai 264000, Shandong, China.
Objective: To analyze the epidemiological characteristics of measles, mumps, and rubella (MMR) between 2014 and 2021 and identify potential strategies and measures for the prevention and control of MMR in China.
Methods: Data on MMR was obtained from China's National Notifiable Disease Reporting System for the period from 2014 to 2021. Spatiotemporal distributions were analyzed using SaTScan; temporal trends were analyzed using JoinPoint; and clusters were visualized using ArcGIS.
Przegl Epidemiol
December 2024
Zakład Epidemiologii Chorób Zakaźnych i Nadzoru, Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy.
Background: Mumps, also known as Sudden parotitis, is a viral disease whose main source of infection is the sick/infected person. It posed a serious public health threat in Poland before the introduction of mandatory vaccination. In 2003, Poland introduced the Immunization Program, which included a two-dose vaccination against mumps as part of the MMR (measles, mumps and rubella) vaccine for all children.
View Article and Find Full Text PDFVaccine
January 2025
University of Zagreb, Centre for research and knowledge transfer in biotechnology, Rockefeller Street 10, 10 000 Zagreb, Croatia. Electronic address:
Mumps epidemics highlight the necessity for new live mumps vaccines. For vaccine candidate neurosafety assessment, the most commonly used test is the rat-based neurovirulence test (RNVT). Its main experimental and ethical deficiency is the results dispersion which requires large number of animals to obtain statistically relevant results.
View Article and Find Full Text PDFJ Med Virol
August 2024
Department of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Przegl Epidemiol
May 2024
National Institute of Public Health NIH - National Research Institute, Department of Epidemiology of Infectious Diseases and Surveillance Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy, Zakład Epidemiologii Chorób Zakaźnych i Nadzoru.
Introduction: Mumps is a contagious viral disease occurring mainly in children, the source of infection being the sick/infected person. Since 2003, vaccination against mumps has been mandatory in Poland, performed according to a two-dose schedule. As part of the Public Health Immunization Program (PSO), the MMR combination vaccine (against measles, mumps and rubella) is used for the entire population of children.
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