Solutions of calcium chloride in mixed water and formamide are excellent electrolytes for capacitive charge storage in partially oxidised carbon nanotubes at unprecedented sub-zero-temperatures (e.g. 67% capacitance retention at -60 °C).
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http://dx.doi.org/10.1039/c5cc03048j | DOI Listing |
Environ Geochem Health
January 2025
Nuclear Technology Research and Development Center, Thailand Institute of Nuclear Technology, Nakhon Nayok, 26120, Thailand.
The present study aimed to investigate the hydrogeochemical patterns and contamination of the radiogeology, especially radon activity, related to geothermal aquifer properties and to perform a risk assessment of annual effective doses covering all hydrothermal spring attractions in Southern Thailand. Radon is an established lung carcinogen; especially longer term exposure to radioactive radon through inhalation could be a cause of lung cancer risk. Altogether 22 hydrothermal spring samples were collected from the six hydrothermal provinces in Southern Thailand in early November of 2023.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Huddersfield, Huddersfield, Yorkshire, United Kingdom.
Background: Alzheimer's Disease research lacks a suitable model to match the sporadic version of Alzheimer's Disease (SAD). We a propose a model that will use 7PA2 cells which is a CHO modified to express the V717F mutation for APP (Indiana mutation). The 7PA2 cells will then be placed inside alginate microbeads to produce a factory that constantly produces amyloid species.
View Article and Find Full Text PDFFood Funct
January 2025
School of Food and Health, Beijing Technology and Business University, Beijing 100048, China.
In this study, a walnut peptide (WP) with calcium-binding capacity was prepared using a combination of alkalase and neutrase. The conditions for the preparation of walnut peptide calcium chelate (WP-Ca) were optimised (a peptide/calcium chloride ratio of 1 : 4 for 70 min at 50 °C and pH 9.5).
View Article and Find Full Text PDFInt J Biol Sci
January 2025
Faculty of Health Sciences, University of Macau, Taipa, Macau.
Ion channels play a crucial role in cardiac functions, and their activities exhibit dynamic changes during heart development. However, the precise function of ion channels in human heart development remains elusive. In this study, we utilized human embryonic stem cells (hESCs) as a model to mimic the process of human embryonic heart development.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
National Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
TMEM16A, a key calcium-activated chloride channel, is crucial for many physiological and pathological processes such as cancer, hypertension, and osteoporosis, etc. However, the regulatory mechanism of TMEM16A is poorly understood, limiting the discovery of effective modulators. Here, we unveil an allosteric gating mechanism by presenting a high-resolution cryo-EM structure of TMEM16A in complex with a channel inhibitor that we identified, Tamsulosin, which is resolved at 2.
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