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Postprandial effects on arterial stiffness parameters in healthy young adults. | LitMetric

Postprandial effects on arterial stiffness parameters in healthy young adults.

Vasc Med

Baylor College of Medicine, Houston, TX, USA The Methodist Hospital-Michael E Debakey Heart and Vascular Institute, Houston, TX, USA Michael E Debakey Veterans Affairs Hospital, Houston, TX, USA.

Published: December 2015

AI Article Synopsis

  • Postprandial lipemia is linked to issues with the endothelial function, which can lead to increased stiffness in arteries.
  • A study was conducted on 19 healthy young adults to examine how eating a high-fat meal affects arterial stiffness, using specific methods to measure it.
  • The results showed that while standard measures of arterial stiffness didn’t change significantly after eating, the arterial distension period decreased and the carotid artery area curves were steeper, suggesting that the distension period might be a better indicator of arterial stiffness in this group.

Article Abstract

Postprandial lipemia has been associated with acute endothelial dysfunction. Endothelial dysfunction, in turn, is associated with increased arterial stiffness. However, the relationship between postprandial lipemia and acute changes in arterial stiffness has not been extensively investigated. Therefore, we conducted a pilot study on the effects of postprandial lipemia on arterial stiffness in 19 healthy young adults before and after consumption of a high-fat mixed meal. Arterial stiffness was assessed locally with echo-tracking carotid arterial strain (CAS) and globally with carotid-femoral pulse wave velocity (PWV). As assessed by these two benchmark parameters, arterial stiffness did not differ significantly postprandially. However, the arterial distension period (ADP) was significantly lower 2 hours after mixed meal ingestion. In addition, slopes of carotid artery area (CAA) curves were significantly steeper postprandially. Therefore, we concluded that ADP may be a more sensitive marker of arterial stiffness in healthy young adults when compared to PWV and CAS.

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Source
http://dx.doi.org/10.1177/1358863X15587044DOI Listing

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