[Peculiarities of the clinical course of ulcerative colitis, depending on the spectrum of cross-linked autoantibodies from the same family to antigens of neutrophils].

There were found that patients with ulcerative colitis (UC) in the presence of two types of autoantibodies to antigens of neutrophils is observed in less pronounced activity in the course of the disease compared with those patients with a spectrum of autoantibodies one of the wider family. The patients with three or more types of antibodies from the same family, cross-linked, ware accompanied by an increase in clinical and endoscopic disease activity. It is shown that a--greater range of autoantibodies one family determines not only the degree of activity of the YAK, but the nature and intensity of its extraintestinal manifestations. Identify different spectra of autoantibodies one family to antigens of neutrophils, cross-linked, allows us to predict the nature of the disease in each particular patient.