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An investigation of antiproliferative and antioxidant properties of crude extracts from Sedum nicaeense All. (Crassulaceae).
Pak J Pharm Sci
January 2025
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.
This study evaluated the antioxidant and antiproliferative effects of aqueous, ethanolic and methanolic extracts of Sedum nicaeense flowers and leaves. The MTT assay assessed cytotoxicity against colorectal cancer cells (Caco-2, HCT-116), breast cancer cells (T47D, MCF-7) and normal fibroblasts (MRC-5), while the ferric-reducing antioxidant power (FRAP) assay measured antioxidant capacity. Essential oils from flowers and leaves were analyzed using gas chromatography-mass spectrometry (GC-MS).
View Article and Find Full Text PDFPeruvian medical residency selection: a portrayal of scores, distribution, and predictors of 28,872 applicants between 2019 and 2023.
BMC Med Educ
January 2025
Centro de Investigación de Educación Médica y Bioética - EDUCAB-UPT, Facultad de Ciencias de la Salud, Universidad Privada de Tacna, Tacna, Peru.
Background: Residency selection is crucial for enhancing the healthcare workforce. Most research on this topic arises from the global north, leaving a gap from the global south perspective. Hence, this study aimed to evaluate factors associated with the Peruvian National Residency Examination (ENARM) in Peruvian applicants.
View Article and Find Full Text PDFCausal effects of retinol and vitamin D on tongue cancer risk: a mendelian randomization study.
BMC Oral Health
January 2025
Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Background: Previous studies have indicated that retinol and vitamin D may be associated with the oncogenesis of tongue cancer. Therefore, we aimed to assess the causal relationships of retinol and vitamin D with the risk of tongue cancer using the two-sample Mendelian randomization (MR) method.
Methods: Single nucleotide polymorphisms (SNPs) related to retinol, vitamin D and tongue cancer were obtained from the up-to-date genome-wide association study (GWAS) catalogue, which was screened for instrumental variables (IVs).
Gliricidia sepium (Jacq.) Kunth. ex. Walp. leaves-derived biogenic nanohydrogel accelerates diabetic wound healing in rats over 21 days.
Burns
December 2024
Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo 11562, Egypt.
This study focused on the potential of Gliricidia sepium (Jacq.) Kunth. ex.
View Article and Find Full Text PDFDietary purslane (Portulaca oleracea L.) leaf powder maintains growth and intestinal health in Oreochromis niloticus under chronic water-borne cadmium exposure by strengthening the gut barriers, modulating the intestinal nutrient transporters, and relieving oxidative stress.
Fish Physiol Biochem
January 2025
Department of Biological Sciences, College of Science, University of Jeddah, P.O. Box 80327, Jeddah 21589, Saudi Arabia.
High cadmium (Cd) concentrations pose a threat to aquatic life globally. This study examined the efficiency of adding purslane (Portulaca oleracea L.) leaf powder (PLP) to Oreochromis niloticus diets on Cd's negative effects.
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