A pigmented lesion of the iris followed up for five years in a 31-year-old female patient with marked progress during the past two years which led to block excision of the formation. Clinical signs (growth, vascularization, pigmentation and blood in the angle) as well as results of auxiliary examinations (ultrasound, fluorescein angiography) suggested a malignant lesion. However, histological examination provided evidence of the benign nature of the formation. Contemporary diagnostic non-invasive methods cannot decide definitely on the nature of a progressing neoplasm of the iris. The authors recommend long-term patient observation of these patients and surgery only in fully indicated cases.
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