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http://dx.doi.org/10.1542/peds.2015-0688 | DOI Listing |
Unlabelled: Eastern equine encephalitis virus (EEEV) is an arthropod-borne, positive-sense RNA alphavirus posing a substantial threat to public health. Unlike similar viruses such as SARS-CoV-2, EEEV replicates efficiently in neurons, producing progeny viral particles as soon as 3-4 hours post-infection. EEEV infection, which can cause severe encephalitis with a human mortality rate surpassing 30%, has no licensed, targeted therapies, leaving patients to rely on supportive care.
View Article and Find Full Text PDFOrganisms with smaller genomes often perform multiple functions using one multi-subunit protein complex. The Silent Information Regulator complex (SIRc) carries out all of the core functions of heterochromatin. SIR complexes first drive the initiation and spreading of histone deacetylation in an iterative manner.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Department of Plant and Soil Sciences, University of Pretoria, Hatfield, 0001, Pretoria, South Africa.
In recent decades, natural rangelands have emerged as vital sources of livelihood and ecological services, particularly in Southern Africa, supporting communities in developing regions. However, the escalating global demand for food, driven by a growing human population, has led to the extensive expansion of cultivated areas, resulting in continuous nutrient leaching in rangelands. To ensure the long-term viability of these ecosystems, there is a need to develop effective approaches for managing and monitoring the seasonality of forage quality.
View Article and Find Full Text PDFNat Metab
January 2025
Systems Biology Lab, AIMMS/A-LIFE, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Sci Rep
January 2025
Tianjin Chengjian University, Tianjin, China.
Urban overheating significantly affects thermal comfort and livability, making it essential to understand the relationship between urban form and land surface temperature (LST). While the horizontal dimensions of urban form have been widely studied, the vertical structures and their impact on LST remain underexplored. This study investigates the influence of three-dimensional urban form characteristics on LST, using ECOSTRESS sensor data and four machine learning models.
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