Neuroimmunology and Multiple Sclerosis Unit, Department of Neurology, Dr. Josep Trueta University Hospital, Avda. França s/n, 17007 Girona, Spain; Neurodegeneration and Neuroinflammation Group, Girona Biomedical Research Institute (IDIBGI), Avda. França s/n, 17007 Girona, Spain. Electronic address: