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Creation of the Indigenous Support Line for health system navigation and culturally safe access to care: a quality improvement project.
BMJ Open Qual
December 2024
Alberta Health Services, Edmonton, Alberta, Canada.
Indigenous Peoples face inequities in health and healthcare access due to colonial history and systems. To work towards the Truth and Reconciliation Commission of Canada's Calls to Action and the United Nations Declaration on the Rights of Indigenous Peoples, Alberta Health Services has collaborated with a Wisdom Council of engaged Elders and Indigenous community members to tailor programmes for Indigenous Peoples. The Indigenous Support Line (ISL) was created based on the Wisdom Council's advice to provide an Indigenous-specific concerns line, which later expanded into a telehealth line to address any health questions or access issues, including health system navigation and access to Western and Indigenous health and wellness supports.
View Article and Find Full Text PDFKnowledge of medications for opioid use disorder and associated stigma among primary care professionals.
Ann Med
December 2024
Heritage College of Osteopathic Medicine, Ohio University, Athens, OH.
Background: Medications for opioid use disorder (MOUD) are the gold standard. However, significant barriers limit their use in the primary care setting, including limited knowledge of the medications and stigmatizing attitudes. In this study, we assess knowledge levels among primary care-aligned professionals (PCPs) currently in practice, and whether knowledge of MOUD is associated with stigma and treatment attitudes.
View Article and Find Full Text PDFThe use of coaching in smartphone app-based cognitive behavioral therapy for body dysmorphic disorder.
Internet Interv
June 2024
Massachusetts General Hospital, United States of America.
Article Synopsis
- Body dysmorphic disorder (BDD) is a serious problem that isn't treated enough, and using online therapy could help people get better access to treatment like cognitive behavioral therapy (CBT).
- In a study with 77 adults using a 12-week guided smartphone program for BDD, they sent a lot of messages to their coaches to get support.
- The researchers found three main ways people interacted with their coaches and discovered that younger users tended to communicate less while older users communicated more, and this affected how well they followed the treatment.
Insider Threats to the Military Health System: A Systematic Background Check of TRICARE West Providers.
JMIRx Med
April 2024
UC Institute for Prediction Technology, University of California, Irvine, Orange, CA, United States.
Background: To address the pandemic, the Defense Health Agency (DHA) expanded its TRICARE civilian provider network by 30.1%. In 2022, the DHA Annual Report stated that TRICARE's provider directories were only 80% accurate.
View Article and Find Full Text PDFCo-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat Struct Mol Biol
February 2024
Arvinas, Inc, New Haven, CT, USA.
Article Synopsis
- Targeted protein degradation (TPD) is highlighted as a new therapeutic strategy using PROTAC technology to selectively degrade proteins in cells.
- Researchers discovered small-molecule ligands that specifically target the E3 ligase KLHDC2, expanding the options available for TPD.
- The study reveals how the KLHDC2 E3 ligase forms a dynamic tetrameric structure, which can be influenced by the interaction with substrates and ligands, enhancing our understanding of its functioning and potential applications.
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