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Background: The rupture of intracranial aneurysms (IAs) leads to aneurysmal subarachnoid hemorrhage (aSAH), which is associated with significant disability and mortality rates. This study aims to identify metabolic markers causally linked to the occurrence of IAs and aSAH through Mendelian randomization (MR), thereby offering novel predictive and therapeutic targets.
Methods: We conducted a genome-wide association study (GWAS) on IAs and aSAH, analyzing 1,400 metabolomic indices from the Canadian Longitudinal Study on Aging (CLSA) cohort (n = 8,299).
Effectiveness of Telemedicine in Inflammatory Bowel Disease in Russia: TIGE-Rus (Telemonitoring for IBD Goodness Examination in Russia) Study Protocol of a Randomized Controlled Trial.
J Clin Med
December 2024
Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Moscow 127051, Russia.
: Inflammatory bowel diseases (IBD), associated with a significant burden on patients' lives, are becoming increasingly common. Patients with IBD need continuous treatment and lifelong monitoring, which could be achieved by telemonitoring. Telemonitoring has been shown to be effective in improving outcomes for patients with IBD, and can provide a more convenient and accessible way for patients to receive care.
View Article and Find Full Text PDFPurpose: In response to the need to support health care professionals during the COVID-19 pandemic, an innovative, peer-led discussion group program for medical school faculty, called CIRCLE (Colleague Involved in Reaching Colleagues through Listening and Empathy), was developed at Rutgers Health. This article describes results of a qualitative analysis of the participants' experiences, explores virtual communication platform use during this peer support program, and identifies the program's beneficial elements.
Method: CIRCLE was inaugurated in October 2020 at Rutgers New Jersey Medical School and Rutgers Robert Wood Johnson Medical School using evidence-informed topics.
Balancing landscape values and tourism choices: Integrating participatory mapping and the IPBES Values Typology.
Ambio
January 2025
Department of Geography and Geology, University of Turku, 20014, Turku, Finland.
The United Nations Educational, Scientific and Cultural Organization (UNESCO) Biosphere Reserves aim to balance nature and human coexistence, but increasing tourism challenges landscape management. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) stresses the importance of understanding stakeholder values for effective management of natural spaces through a typology of intrinsic, instrumental, and relational values. This study applies this IPBES typology to tourism preferences in the Archipelago Sea Biosphere Reserve (ABR) using Public Participation Geographic Information Systems (PPGIS).
View Article and Find Full Text PDFDental bur detection system based on asymmetric double convolution and adaptive feature fusion.
Sci Rep
December 2024
School of Mechanical Engineering, Shaanxi University of Technology, Hanzhong, 723001, China.
This study aims to improve the detection of dental burs, which are often undetected due to their minuscule size, slender profile, and substantial manufacturing output. The present study introduces You Only Look Once-Dental bur (YOLO-DB), an innovative deep learning-driven methodology for the accurate detection and counting of dental burs. A Lightweight Asymmetric Dual Convolution module (LADC) was devised to diminish the detrimental effects of extraneous features on the model's precision, thereby enhancing the feature extraction network.
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