In this issue of Structure, Bourne et al. (2015) report X-ray structures of acetylcholine binding protein with two fast-acting phycotoxins from the pinnatoxin family. The results may pave the way for development of new CNS-penetrant and subtype-selective nAChR antagonists.
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http://dx.doi.org/10.1016/j.str.2015.05.008 | DOI Listing |
J Hazard Mater
December 2024
Center for Marine Studies, Federal University of Paraná, Pontal do Paraná, Brazil.
Microplastics (MP) are suitable substrates for the colonization of harmful microalgal cells and the adsorption of their lipophilic compounds including phycotoxins. Moreover, such interactions likely change as physical-chemical characteristics of the MP surface are gradually modified during plastic degradation in aquatic environments. Using a combination of innovative laboratory experiments, this study systematically investigated, for the first time, the influence of various MP characteristics (polymeric composition, shape, size, and/or surface roughness) on its capacity to carry both living harmful algal cells and dissolved phycotoxins.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
University of Victoria, 3800 Finnerty Road, Victoria, BC V8W 2Y2, Canada. Electronic address:
Marine pollution poses significant risks to both marine ecosystems and human health, requiring effective monitoring and control measures. This study presents the Ocean Pollution Monitoring System (OPMS), a web application designed to visualize the seasonal and annual fluctuations of marine pollutants along coastal regions in Canada. The pollutants include fecal coliform and biotoxins such as paralytic shellfish poisoning (PSP), and amnesic shellfish poisoning (ASP).
View Article and Find Full Text PDFEnviron Int
December 2024
National Institute for Minamata Disease, Minamata, Kumamoto 867-0008, Japan.
Harmful Algae
January 2025
Bachok Marine Research Station, Institute of Ocean and Earth Sciences, University of Malaya 16310 Bachok, Kelantan, Malaysia. Electronic address:
The benthic pennate diatom Nitzschia navis-varingica, known for producing domoic acid (DA) and its isomers, is widely distributed in the Western Pacific (WP) region. To investigate the genetic differentiation and gene flow patterns among the populations in the WP, the genetic diversity of 354 strains of N. navis-varingica was analysed using two nuclear-encoded rDNA loci: the large subunit rDNA (LSU rDNA) and the internal transcribed spacer 2 (ITS2).
View Article and Find Full Text PDFHarmful Algae
January 2025
Key Laboratory of Testing and Evaluation for Aquatic Product Safety and Quality, Ministry of Agriculture and Rural Affairs, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, 266071, China; State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, 266071, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao Marine Science and Technology Center, Qingdao, Shandong, 266237, China. Electronic address:
Gymnodinium catenatum is a widely distributed toxic marine dinoflagellate that produces paralytic shellfish toxins (PSTs). It is prone to causing algal blooms and poses a serious threat to the shellfish industry and human health. Previous studies have shown that when algal blooms occur, shellfish can accumulate PSTs in their bodies due to filtration.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!