Objectives: to assess the trends of foodborne diseases in respect of the abolition of food handler certification by Italian Regions.
Design: rates of foodborne diseases recorded before and after the abolition of food handler certification were compared.
Setting And Participants: the study included notifications collected in Italy through the national infectious disease surveillance system between 1996 and 2009.
Main Outcome Measures: annual rates of seven main foodborne diseases.
Results: a significant reduction in notifications of foodborne diseases occurred in most Italian Regions in the years after the abolition of the food handler certification.
Conclusions: the abolition of food handler certification coincided with no increase in the overall estimated incidence of foodborne diseases in the Italian population. Furthermore, the temporal and spatial patterns of notification rates suggest the possibility that other key factors have contributed to this result, including the heterogeneity of the surveillance system performance.
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J Agric Food Chem
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Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, National Engineering Laboratory for Industrial Enzymes, Tianjin University of Science and Technology, Tianjin 300457, P. R. China.
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INRAE, Université de Clermont-Ferrand, VetAgroSup, Saint Genès Champanelle, France; Bordeaux Sciences Agro, Gradignan, France.
Nat Commun
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Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
In Parkinson's disease (PD), motor dysfunctions only become apparent after extensive loss of DA innervation. This resilience has been hypothesized to be due to the ability of many motor behaviors to be sustained through a diffuse basal tone of DA; but experimental evidence for this is limited. Here we show that conditional deletion of the calcium sensor synaptotagmin-1 (Syt1) in DA neurons (Syt1 cKO mice) abrogates most activity-dependent axonal DA release in the striatum and mesencephalon, leaving somatodendritic (STD) DA release intact.
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