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Psychosocial situation, burden, and unmet needs among informal caregivers prior to hematopoietic stem cell transplantation: a systematic review of quantitative and qualitative data.
Support Care Cancer
January 2025
Nursing Department, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Yuelu District, Hexi District, Changsha, Hunan, China.
Background: Informal caregivers may face challenges, especially during the pre-transplant phase. We have learned about the challenges faced by informal caregivers during hematopoietic stem cell transplantation; there is a lack of consensus about the challenges faced by them before transplantation. We identified the psychosocial well-being of informal caregivers to patients before hematopoietic stem cell transplantation.
View Article and Find Full Text PDFIdentifying Patients at Risk for a Facility Discharge Following Elective Total Joint Arthroplasty Using Preoperative Clinical Findings and Patient-Reported Outcome Scores.
J Arthroplasty
January 2025
Hartford Healthcare Bone and Joint Institute, 32 Seymour Street, Hartford, CT 06106; Orthopaedic Associates of Hartford, 31 Seymour Street, Hartford, CT 06106.
Introduction: Facility discharges following an elective, primary, total joint arthroplasty are infrequent, but are associated with poor outcomes and significant cost. Therefore, investigating ways to identify patients most likely to be discharged to a facility could improve patient care, reduce costs, and potentially lead to strategies to mitigate these risks.
Methods: A total of 3,198 patients who underwent a total hip or knee arthroplasty between June 2021 and June 2023 were included in this study.
High-intensity home-based rehabilitation in a Medicare accountable care organization.
Am J Manag Care
January 2025
Department of Orthopedic Surgery, Duke University School of Medicine, 311 Trent Dr, Durham, NC 27710. Email:
Objectives: Patients are often discharged to a skilled nursing facility (SNF) for postacute rehabilitation. Functional outcomes achieved in SNFs are variable, and costs are high. Especially for accountable care organizations (ACOs), home-based postacute rehabilitation offers a high-value option if outcomes are not compromised.
View Article and Find Full Text PDFDecoding the Role of Kinesin Superfamily Proteins in Glioma Progression.
J Mol Neurosci
January 2025
Gilgamesh Ahliya University, Baghdad, Iraq.
Glioma is a highly aggressive and invasive brain tumor with limited treatment options, highlighting the need for novel therapeutic approaches. Kinesin superfamily proteins (KIFs) are a diverse group of motor proteins that play essential roles in cellular processes such as mitosis, intracellular transport, and signal transduction, all of which are crucial for tumorigenesis. This review focuses on the multifaceted role of KIFs in glioma, examining their clinical relevance, contribution to tumor progression, and potential as therapeutic targets.
View Article and Find Full Text PDFNanoenzyme-based sensors for the detection of anti-tumor drugs.
Mikrochim Acta
January 2025
Public Health School, Mudanjiang Medical University, Mudanjiang, China.
Natural enzymes are a class of biological catalysts that can catalyze a specific substrate. Although natural enzymes have catalytic activity, they are susceptible to the influence of external environment such as temperature, and storage requirements are more stringent. Since the first discovery of magnetic FeO nanoparticles with peroxidase-like activity in 2007, the research on nanoenzymes has entered a rapid development stage.
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