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Leukemic myeloblasts with erythrophagocytosis.
Blood
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Esoterix Pathology Practice Group.
Erythrophagocytosis of myeloblasts in acute myeloid leukaemia exhibiting chromosome 8p abnormality and extramedullary disease.
Br J Haematol
July 2015
Oncology Cytogenetics, The Christie Pathology Partnership, The Christie NHS Foundation Trust, Manchester, UK.
A tetraploid minimally differentiated acute myeloblastic leukemia with extensive erythrophagocytosis: a case report and literature review.
Int J Hematol
December 2012
Institute of Hematology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, 030001, Shanxi, People's Republic of China.
Tetraploidy is a rare chromosome number aberration in de novo acute myeloid leukemia (AML), and may be associated with erythrophagocytosis by leukemic blast cells. We report a 48-year-old female patient with minimally differentiated acute myeloblastic leukemia (AML-M0) exhibiting tetraploidy and erythrophagocytosis. The karyotype was 46,XX[2]/92,XXXX[18].
View Article and Find Full Text PDFSecondary acute monocytic leukemia with a translocation t(8;16)(p11;p13): case report and review of the literature.
Leuk Lymphoma
March 2004
Department of Medicine, Kagawa Prefectural Central Hospital, Kagawa, Japan.
Acute myeloblastic leukemia cases carrying the translocation t(8;16) (p11;p13) are characterized by the M4 and M5 subtypes, erythrophagocytosis by the blast cells and a poor prognosis, suggesting a new clinical entity. The t(8;16) fuses the MOZ gene which encodes a histone acetyltransferase, located on 8p11 with the CBP gene which also encodes a histone acetyltransferase, located on 16p13, and recent reports suggested that the chimeric transcription MOZ-CBP is essential for leukemogenesis. A 68-year-old woman who had been treated mainly with paclitaxel and carboplatin for preceding ovarian cancer was admitted to our hospital, complaining of right breast mass.
View Article and Find Full Text PDFErythrophagocytosis by myeloid cells in a patient with myeloproliferative disorder.
Yonsei Med J
October 2003
Department of Laboratory Medicine, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.
This report documents a case of myeloid erythrophagocytosis in a patient with myeloproliferative disorder. The patient had pancytopenia and his marrow was hyperplastic with erythrophagocytosis by myeloid cells of various stages, including myeloblasts. He was diagnosed to have a prefibrotic stage of chronic idiopathic myelofibrosis.
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