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Pyomyositis Due to a Rare Fungal Infection-Findings on 68Ga-NOTA UBI PET/CT.
Clin Nucl Med
December 2024
From the All India Institute of Medical Sciences, New Delhi, Delhi, India.
It is very rare to see fungal arthritis and pyomyositis in immunocompetent patients. Here, we report a case of Scedosporium infection in an immunocompetent patient with interesting 18F-FDG PET/CT and 68Ga-NOTA UBI PET/CT findings.
View Article and Find Full Text PDFFungal ball due to a species of the Scedosporium apiospermum complex in a post-tuberculosis patient.
Rev Iberoam Micol
December 2024
Universidad de Buenos Aires, Facultad de Medicina, Departamento de Microbiología y Parasitología Médica, Buenos Aires, Argentina. Electronic address:
Background: Scedosporium species are considered emerging pathogens causing illness in immunocompetent and immunocompromised hosts.
Case Report: A case of non-invasive pulmonary (fungal ball) infection by Scedosporium apiospermum complex in a 49-year-old female with bronchiectasis and cavities secondary to tuberculosis is described. The patient had a history of three years of cough and hemoptysis.
Construction of versatile plastic-degrading microbial consortia based on ligninolytic microorganisms associated with agricultural waste composting.
Environ Pollut
November 2024
Unit of Microbiology, Department of Biology and Geology, CITE II-B, Agrifood Campus of International Excellence ceiA3, CIAIMBITAL, University of Almeria, 04120, Almeria, Spain.
Article Synopsis
Elucidating the augmented resistance profile of Scedosporium/Lomentospora species to azoles in a cystic fibrosis mimic environment.
J Antimicrob Chemother
November 2024
Departamento de Microbiologia Geral, Laboratório de Estudos Avançados de Microrganismos Emergentes e Resistentes (LEAMER), Instituto de Microbiologia Paulo de Góes (IMPG), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil.
Background: Scedosporium/Lomentospora species are ranked as the second most frequently isolated filamentous fungi from cystic fibrosis (CF) patients. Previously, we demonstrated that the minimum inhibitory concentration (MIC) for voriconazole and posaconazole increased when performed on a mucin-containing synthetic CF sputum medium (SCFM) compared to the standard medium, RPMI-1640. In this study, we have expanded the MIC comparison to four additional azoles and investigated characteristics linked to azole resistance in Scedosporium apiospermum, Scedosporium minutisporum, Scedosporium aurantiacum and Lomentospora prolificans.
View Article and Find Full Text PDFExploring the Siderophore Portfolio for Mass Spectrometry-Based Diagnosis of Scedosporiosis and Lomentosporiosis.
ACS Omega
November 2024
Laboratory of Molecular Structure Characterization, Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 142 00 Prague, Czechia.
Article Synopsis
- Siderophores are iron-scavenging compounds secreted by certain fungal strains during their growth, playing a role in their virulence and potential use as clinical biomarkers for invasive infections like scedosporiosis and lomentosporiosis.
- The strains produced various types of siderophores, with -methyl-coprogen B being the most abundant and secreted faster, particularly under conditions of limited iron and zinc, which may increase their virulence.
- Additionally, two new cyclic peptides were identified using advanced sequencing, and the detection methods for coprogens were refined, suggesting they could be valuable tools for diagnosing these infections in clinical settings.
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