AI Article Synopsis
- This study looked at two different ways to do a medical procedure called exchange transfusion (ET) to help treat jaundice in newborn babies.
- The researchers found that the new fully automated method worked better and faster than the traditional method for lowering bilirubin levels in the babies' blood.
- Both methods were safe, meaning they didn't have extra risks of complications for the babies while the new method also made the treatment more comfortable for them.
Article Abstract
Objectives: The purpose of this study was to compare the efficacy and safety of two different catheterization techniques of exchange transfusion (ET) used in the therapy of newborn jaundice: fully automated two-way ET technique and the classical one-way ET.
Patients And Methods: The study included babies at gestational age of >34 weeks. In total, 107 ETs were performed on 86 babies. Totally, the umbilical vein (UV) group included 54 babies having undergone 69 ETs and the UV/UA group included 32 babies having undergone 38 ETs.
Results: The declines in bilirubin levels right after ET (p = 0.018) and 8 h after ET (p = 0.014) were higher in the fully automated UV/UA technique than in the classical UV technique. Furthermore, the duration of intensive phototherapy following ET was shorter in the UV/UA method than in the UV method (p = 0.003). There was no difference between the two methods in terms of ET-associated complications (p = 0.927).
Conclusions: In neonatal hyperbilirubinemia, ET with fully automated UV/UA technique is more efficient than the classical ET technique, causing no additional side-effects. It is also more physiological than the classical technique, since it minimizes the fluctuations in the blood volume and intravascular pressure during ET.
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| http://dx.doi.org/10.3109/14767058.2015.1045864 | DOI Listing |
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