Effectively preventing and treating chronic diseases through health behavior changes often require intensive theory- and evidence-based intervention including long-term maintenance components. We assessed the efficacy of theory-based maintenance approaches varying by dose for persistently performing resistance training (RT) with the hypothesis that a higher-dose social cognitive theory (SCT) approach would produce greater RT adherence than lower-dose Standard. The Resist-Diabetes study first established 2×/week resistance training (RT) in a 3-month supervised intervention in older (50-69 years, N = 170), overweight to obese (BMI 25-39.9 kg/m(2)) previously inactive adults who fit prediabetes criteria (fasting glucose concentration = 95-125 mg/dl; oral glucose tolerance test 2-h glucose concentration = 140-199 mg/dl or both). After the supervised phase, participants (N = 159) were then randomly assigned to one of two conditions for transition (3 weeks) and then RT alone in community settings for extended contact, maintenance (6 months), and then no contact (6 months). SCT featured continued tailored, interactive personal, and web-based check-ups focused on RT, self-regulation, and a barrier/strategies approach. Standard involved low-dose, generic personal, and web-based check-ups within the same theoretical approach. SCT and Standard both resulted in similar RT, 2×/week adherence during maintenance (74.4 %) and no-contact phases (53.1 %). Cost analysis indicated the Standard intervention for transition and maintenance was inexpensive ($160). Standard can be translated into practice with the potential for continuous contact and persistence in RT beyond the typical program maintenance phase.
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http://dx.doi.org/10.1007/s13142-015-0304-5 | DOI Listing |
PLoS One
January 2025
National Institute of Public Health of Mexico, Center for Evaluation and Surveys Research, Cuernavaca, Morelos, Mexico.
Introduction: Tackling the inertia of growing threat of antimicrobial resistance (AMR) requires changes in how antibiotics are prescribed and utilized. The monitoring of antimicrobial prescribing in hospitals is a critical component in optimizing antibiotic use. Point prevalence surveys (PPSs) enable the surveillance of antibiotic prescribing at the patient level in small hospitals that lack the resources to establish antimicrobial stewardship programs (ASP).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Background: Excessive high-fat diet (HFD) consumption develops the obese pre-diabetic condition, which initiates neuroinflammation and numerous brain pathologies, resulting in cognitive decline (1). A cinnamamide derivative compound (2i-10) is recently identified as a novel myeloid differentiation factor 2 (MD-2) inhibitor, and has been shown to attenuate inflammation via toll-like receptor 4 (TLR4) signaling pathway (2). However, the effects of 2i-10 on the neuroinflammation, brain pathologies and cognitive function in the obese pre-diabetic rats have never been studied.
View Article and Find Full Text PDFEthics Hum Res
January 2025
Assistant professor in the Department of Equity, Ethics, and Policy, and in the Department of Social Studies of Medicine, at McGill University.
This article brings a philosophical perspective to bear on issues of research ethics governance as it is practiced and organized in Canada. Insofar as the processes and procedures that constitute research oversight are meant to ensure the ethical conduct of research, they are based on ideas or beliefs about what ethical research entails and about which processes will ensure the ethical conduct of research. These ideas and beliefs make up an epistemic infrastructure underlying Canada's system of research ethics governance, but, we argue, extensive efforts by community members to fill gaps in that system suggest that these ideas may be deficient.
View Article and Find Full Text PDFInt J Appl Basic Med Res
November 2024
Department of Homoeopathic Materia Medica, Karnataka KLE Medical College and Hospital, Belagavi, Karnataka, India.
Background: Active learning strategies (ALSs) in medical education are valued for their effectiveness but face adoption challenges among educators, underscoring the need for a deeper understanding of their implementation and impact.
Aim: The aim of the study was to investigate the perceptions of medical educators regarding the effectiveness and challenges of ALS through mentor-learner (ML) web-based discussions.
Settings And Design: The retrospective cross-sectional study analyzed data from 32 medical educators enrolled in the Foundation for Advancement of International Medical Education Research course at Christian Medical College, Ludhiana.
J Hypertens
February 2025
Research Centre for Exercise Detoxification, College of Physical Education, Southwest University, Chongqing 400715, China.
Background And Aims: Exploring the effect of different isometric resistance training (IRT) on improving blood pressure, so as to provide important reference for the design of aerobic exercise prescription for IRT to improve blood pressure.
Methods: Forty eight overweight or obese college students with irregular exercise habits were randomly divided into four groups and underwent exercise intervention three times a week for a total of 6 weeks. Cardiovascular changes were evaluated before the first and 18th exercise sessions, as well as 0, 30, and 60 min after exercise.
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