A review was conducted of 118 episodes of serratia bacteremia in cancer patients during a 16-year period. The infection occurred most commonly in patients with acute leukemia. Most patients acquired the infection in the hospital, and 61% had received antibiotic therapy during the preceding 10 days. Fever occurred in 90% of cases and shock in 18%. Thirty-eight percent of patients had concomitant pneumonia. Patients with shock, pneumonia, or hemorrhage had a substantially poorer prognosis. The response rate was 75% for patients who received appropriate antibiotics, 22% for those who received inappropriate antibiotics, and 29% for those who received no antibiotics. Patients who continued to have positive blood culture results while receiving appropriate antibiotic therapy had a poor diagnosis. Patients who received only an aminoglycoside had the poorest response rate among those who received appropriate therapy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/clinids/11.6.912 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metronidazole-Associated Peripheral Neuropathy in a Patient With End-Stage Renal Failure.
Cureus
December 2024
Internal Medicine, Eastern Virginia Medical School, Norfolk, USA.
Metronidazole is a broad-spectrum antimicrobial that is associated with 0.16% 100-day incidence rates for peripheral neuropathy. In this report, we present an interesting and rare presentation of peripheral neuropathy secondary to metronidazole use for bacteremia and sepsis in a patient with end-stage renal failure.
View Article and Find Full Text PDFCarbapenem-Resistant Bacteremia in Pediatric Patients in Latin America and the Caribbean: A Systematic Review and Meta-Analysis.
Antibiotics (Basel)
November 2024
Instituto de Efectividad Clínica y Sanitaria, Buenos Aires 1414, Argentina.
Data on the health impact of carbapenem-resistant bloodstream infections (CRE-BSIs) in pediatric populations from Latin America and the Caribbean (LAC) are limited. This systematic review aims to examine the demographic, clinical, and microbiological aspects and resource utilization of this infection in children from this region. This systematic review investigates the impact of CRE-BSIs in pediatric populations across LAC.
View Article and Find Full Text PDFArticle Synopsis
- Recent research has classified a specific bacterial strain as low-risk for producing a certain enzyme affecting antibiotic efficacy, but there is limited data on how antibiotic choices impact patient outcomes in bacteremia.
- This study focused on comparing clinical outcomes between patients treated with AmpC-directed β-lactam therapy and narrower spectrum therapies for ceftriaxone-susceptible bacteremia, reviewing records over an 8-year period from seven hospitals.
- Results indicated that while carbapenem therapy showed trends toward lower mortality and longer treatment duration, these differences weren't statistically significant, emphasizing the need for proper antibiotic stewardship to avoid the development of drug-resistant bacteria.
A Novel Approach to Identifying Appropriate Candidates for Transvenous Lead Extraction.
J Cardiovasc Electrophysiol
December 2024
Cardiovascular Institute, North Shore University Hospital, Northwell Health, Manhasset, New York, USA.
Background: The need for transvenous lead extractions (TLEs) in the setting of cardiac implantable electronic device-(CIED) related infections continues to rise. Delays in referral for TLE in this setting are common and are associated with increased mortality.
Objective: To describe the outcomes of a comprehensive approach, including an electronic medical record (EMR)-based notification algorithm designed to identify patients with active CIED-related infections to facilitate timely TLE.
Non-accidental Trauma Masquerading As Feeding Intolerance in a Six-Month-Old Female.
Cureus
October 2024
Pediatric Neurology, Ponce Health Sciences University, Ponce, PRI.
Article Synopsis
- A six-month-old girl showed signs of feeding intolerance, fever, and leg swelling, leading to the discovery of multiple fractures, which raised suspicions of non-accidental trauma.
- Blood tests indicated an infection with a ceftriaxone-resistant bacteria, requiring a 10-day antibiotic treatment.
- The case emphasizes the need for careful assessment of potential abuse in infants who have unexplained fractures and infections.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!