Computerized optical image analysis is a variant of using computerized analysis of images of study objects recorded by optical methods. This review covers the literature and our own data on computer analysis of optical images of microbial origin. It is concluded that the use of this type of analysis in microbiology makes it possible to accelerate, objectify, and automate many conventional microbiological methods, as well as opens up new possibilities for studying single cells.
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J Med Internet Res
January 2025
Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Background: Clinical decision support systems leveraging artificial intelligence (AI) are increasingly integrated into health care practices, including pharmacy medication verification. Communicating uncertainty in an AI prediction is viewed as an important mechanism for boosting human collaboration and trust. Yet, little is known about the effects on human cognition as a result of interacting with such types of AI advice.
View Article and Find Full Text PDFAdv Mater
January 2025
State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques, Guangdong Engineering Technology Research and Development Centre of Special Optical Fiber Materials and Devices, School of Physics and Optoelectronics, South China University of Technology, Guangzhou, 510641, China.
Broadband near-infrared (NIR) fiber arrays are highly desirable for multiplexed fluorescence endoscopic, however, there is a challenge for the development of miniature light sources with highly efficient broadband NIR emissions. Here the synthesis of a MgAlO:Cr nanocrystal-glass composite (NGC) with an Cr-clusters-induced broadband NIR emission possessing is presented and external quantum efficiency of 44% and a full width at half maximum of 297 nm, and the NGC fiber is further fabricated through a template solidification strategy, resulting in the construction of an all-fiber coupling system by fusing them with commercial quartz fiber that achieves an optical coupling efficiency of 95.2%.
View Article and Find Full Text PDFMov Disord
January 2025
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Background: Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring.
Objective: We set out to investigate the relationship between optic disc pallor measured in fundoscopy images and both prevalent and incident PD.
Methods: We analyzed color fundus photographs from 787 UK Biobank participants: 89 with prevalent PD, 317 with incident PD, and 381 age- and sex-matched controls.
Chemistry
January 2025
Kyoto University: Kyoto Daigaku, Graduate Schools of Pharmaceutical Sciences, 46-29, Yoshidashimoadachi-cho, Sakyo-ku, 606-8501, Kyoto, JAPAN.
Novel circularly-polarized-luminescence (CPL) materials were designed and synthesized by integrating the intrinsic chirality of helicene with the acid/base-responsive properties of fluorescein. The synthesized helicene-fluorescein hybrids exhibit reversible switching between blue fluorescence under neutral conditions and red fluorescence under basic conditions. Furthermore, these hybrid compounds demonstrate unique chiroptical switching behavior with a rare base-triggered CPL sign inversion, where (P)-isomers show a negative CPL signal around 450 nm under neutral conditions and a positive signal around 620 nm under basic conditions, with three-fold enhanced dissymmetry factors (|glum|) under basic conditions.
View Article and Find Full Text PDFAdv Mater
January 2025
School of Optics and Photonics, Beijing Institute of Technology, Beijing, 100081, China.
Room-temperature operation or high-operation temperature (HOT) is essential for mid-wave infrared (MWIR) optoelectronics devices providing low-cost and compact systems for numerous applications. Colloidal quantum dots (CQDs) have emerged as a rising candidate to enable photodetectors to operate at HOT or room temperature and develop the next-generation infrared focal plane array (FPA) imagers. Here, band-engineered heterojunctions are demonstrated to suppress dark current with well-passivated mercury telluride (HgTe) CQDs enabling room-temperature MWIR imaging by single-pixel scanning and 640 × 512 FPA sensitive thermal imaging above 250 K.
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