An integrated and portable Raman analyzer featuring an inverted probe fixed on a motor-driving adjustable optical module was designed for the combination of a microfluidic system. It possesses a micro-imaging function. The inverted configuration is advantageous to locate and focus microfluidic channels. Different from commercial micro-imaging Raman spectrometers using manual switchable light path, this analyzer adopts a dichroic beam splitter for both imaging and signal collection light paths, which avoids movable parts and improves the integration and stability of optics. Combined with surface-enhanced Raman scattering technique, this portable Raman micro-analyzer is promising as a powerful tool for microfluidic analytics.
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http://dx.doi.org/10.1063/1.4921477 | DOI Listing |
Forensic Sci Int
January 2025
Departamento de Química. Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto. Universidade de São Paulo, Avenida Bandeirantes, 3900, Ribeirão Preto, São Paulo CEP 14040-901, Brazil; Instituto Nacional de Ciência e Tecnologia Ciências Forenses (INCT-Forense), Departamento de Química, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14040-901, Brasil; Programa de Cooperação Acadêmica - Segurança Pública e Ciências Forenses (PROCAD-SPCF), Departamento de Química, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14040-901, Brasil. Electronic address:
Forensic gemstone analysis faces many challenges. One of the most critical aspects of gemological research is the classification of a gemstone. It is necessary to understand the mineral species, purity, origin, and identification of treatments to identify and classify a gem correctly, as well as assign a monetary value to it.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Clinical Research Institute, Department of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, College of Chemistry and Chemical Engineering, College of Energy, College of Physical Science and Technology, and Discipline of Intelligent Instrument and Equipment, Xiamen University, Xiamen 361005 China; Scientific Research Foundation of State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen 361005 China. Electronic address:
As a zoonotic virus, highly sensitive detection of monkeypox virus is crucial for its prevention and control due to its rapid increase in cases worldwide and the extremely high risk of virus transmission. In this paper, based on the principle of antigen-antibody specific recognition, an ultrasensitive resonance Raman biosensing probe was prepared using a molecule with the bifunctionality of resonance Raman effect and capturing antibody; and with the strong affinity of the biotin-streptavidin (Bio-SA) system, Bio-antibody and SA test strips were prepared. To match the T-line of the test strip, a portable Raman instrument with a strip-shaped spot was designed.
View Article and Find Full Text PDFAnal Chem
January 2025
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350117, China.
Multiple myeloma is a hematologic malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Despite therapeutic advancements, there remains a critical need for reliable, noninvasive methods to monitor multiple myeloma. Circulating plasma cells (CPCs) in peripheral blood are robust and independent prognostic markers, but their detection is challenging due to their low abundance.
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
Universidad Autónoma de Nuevo León, Facultad de Ciencias Químicas, Av. Universidad S/N Ciudad Universitaria, San Nicolás de los Garza 66455, Nuevo León, Mexico.
Plastic pollution, particularly from microplastics (MPs) and nanoplastics (NPs), has become a critical environmental and health concern due to their widespread distribution, persistence, and potential toxicity. MPs and NPs originate from primary sources, such as cosmetic microspheres or synthetic fibers, and secondary fragmentation of larger plastics through environmental degradation. These particles, typically less than 5 mm, are found globally, from deep seabeds to human tissues, and are known to adsorb and release harmful pollutants, exacerbating ecological and health risks.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia. Electronic address:
The acidity of historic paper, a property crucial for its preservation, is thought to mainly depend on the type of sizing. However, this research shows that during its degradation, paper acidity increases mainly due to the formation of non-volatile carboxylic acids, which accelerate acid-catalysed hydrolysis. Whether and how this accumulation depends on paper composition has not been studied systematically so far.
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