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Preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia.
Cochrane Database Syst Rev
January 2025
Neonatal Intensive Care Unit, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Background: Esophageal atresia is one of the most common life-threatening congenital malformations and is defined as an interruption in the continuity of the esophagus with or without fistula to the trachea or bronchi. Definitive treatment is surgical ligation of the fistula if present and esophageal end-to-end anastomosis of the two pouches, thereby reconstructing the continuity of the esophagus. During this procedure, the surgeon may choose to either ligate or preserve the azygos vein, a major draining vein for the esophagus and surrounding structures, but no definitive consensus on the matter exists.
View Article and Find Full Text PDFGenetic landscape of congenital pouch colon: systematic review and functional enrichment study.
Pediatr Surg Int
November 2024
Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India.
Article Synopsis
- The study focuses on the genetic underpinnings of congenital pouch colon (CPC), highlighting the lack of research in this area despite extensive clinical documentation.
- A total of 20 cases of CPC and 52 controls were analyzed, revealing multiple genetic variants in 11 significant genes linked to critical functions like mucosal barrier integrity and colonic muscle development.
- The results suggest that validating these findings with larger, diverse clinical samples and functional studies is essential to understand the genetic factors contributing to CPC better.
High flow pial arteriovenous fistula with dural sinus malformation of the posterior circulation.
Childs Nerv Syst
December 2024
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India.
Posterior fossa congenital pial arteriovenous fistulas are rare vascular anomalies associated with high morbidity. These anomalies often present challenges to neurointerventionists due to their complex morphological features. We successfully treated two technically challenging, infratentorial large pial arteriovenous fistulas (AVFs) associated with complete flow steal in the basilar artery.
View Article and Find Full Text PDFRathke Cleft Cysts in Identical Twins.
World Neurosurg
November 2024
Department of Neurosurgery, Birmingham Children's Hospital, Birmingham, United Kingdom.
Rathke cleft cysts are congenital, non-neoplastic sellar cysts derived from remnants of embryonic Rathke pouch. Presentation of Rathke cleft cysts can be incidental; however, in larger cysts, presentation can be with headaches, visual deterioration, and pituitary and endocrine dysfunction. Here we report a rare case of identical twin boys with Rathke cleft cysts, highlighting the likely genetically driven development of cyst in this identical twin and need for cranial imaging in identical twins with anomalies of the brain.
View Article and Find Full Text PDFEctopic thymus in the neonatal period: A case report.
Radiol Case Rep
December 2024
Department of Pediatric Gastroenterology, Second Hospital of Lanzhou University, Lanzhou, China.
The thymus, a vital immune organ in humans, plays a crucial role in the differentiation and development of T cells. Its normal development commences around the fourth week of gestation, originating from the ectoderm of the third branchial cleft and the endoderm of the third parotid pouch. By the 7-8th week of gestation, the primary thymus migrates towards the central axis.
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