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Applying a two-stage generalized synthetic control approach to quantify the heterogeneous health effects of extreme weather events: A 2018 large wildfire in California event as a case study.
Environ Epidemiol
February 2025
Scripps Institution of Oceanography, University of California San Diego, La Jolla, California.
Extreme weather events, including wildfires, are becoming more intense, frequent, and expansive due to climate change, thus increasing negative health outcomes. However, such effects can vary across space, time, and population subgroups, requiring methods that can handle multiple exposed units, account for time-varying confounding, and capture heterogeneous treatment effects. In this article, we proposed an approach based on staggered generalized synthetic control methods to study heterogeneous health effects, using the 2018 California wildfire season as a case study.
View Article and Find Full Text PDFRational Fabrication of Functionally-Graded Surfaces for Biological and Biomedical Applications.
Acc Mater Res
December 2024
The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States.
As a ubiquitous feature of the biological world, gradation, in either composition or structure, is essential to many functions and processes. Taking protein gradation as an example, it plays a pivotal role in the development and evolution of human bodies, including stimulation and direction of the outgrowth of peripheral nerves in a developing fetus. It is also critically involved in wound healing by attracting and guiding immune cells to the site of injury or infection.
View Article and Find Full Text PDFImproving the image quality of short-time bone SPECT using cadmium-zinc-telluride detectors with SwiftScan.
Asia Ocean J Nucl Med Biol
January 2025
Department of Nuclear Medicine, Saitama Medical University Hospital, Saitama, Japan.
Objectives: This study aimed to evaluate the quality and associated quantitative values of bone single-photon emission computed tomography (SPECT) with and without SwiftScan using a semiconductor camera equipped with a cadmium-zinc-telluride detector.
Methods: Ten patients with bone metastases from prostate cancer who underwent list-mode SPECT/computed tomography using a whole-body semiconductor camera participated in this study. A total of 130 metastatic lesions from 10 patients were analyzed.
Prospects for synthetic biology in 21 Century agriculture.
J Genet Genomics
December 2024
Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Plant synthetic biology has emerged as a transformative field in agriculture, offering innovative solutions to enhance food security, provide resilience to climate change, and transition to sustainable farming practices. By integrating advanced genetic tools, computational modeling, and systems biology, researchers can precisely modify plant genomes to enhance traits such as yield, stress tolerance, and nutrient use efficiency. The ability to design plants with specific characteristics tailored to diverse environmental conditions and agricultural needs holds great potential to address global food security challenges.
View Article and Find Full Text PDFMembrane-targeted push-pull azobenzenes for the optical modulation of membrane potential.
Light Sci Appl
January 2025
Center for Nanoscience and Technology, Istituto Italiano di Tecnologia, Milano, 20134, Italy.
We introduce a family of membrane-targeted azobenzenes (MTs) with a push-pull character as a new tool for cell stimulation. These molecules are water soluble and spontaneously partition in the cell membrane. Upon light irradiation, they isomerize from trans to cis, changing the local charge distribution and thus stimulating the cell response.
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