Mycobacterium bovis Enterocolitis in an Immunocompromised Host.

J Pediatr Gastroenterol Nutr

*Department of Pediatrics†Department of Pediatric Infectious Diseases‡Department of Radiology and Biomedical Imaging§Department of Pathology||Department of Pediatric Gastroenterology, Hepatology and Nutrition, University of California, San Francisco¶Department of Surgery, Division of Abdominal Transplantation, Stanford University, School of Medicine, Stanford, CA.

Published: July 2016

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449326PMC
http://dx.doi.org/10.1097/MPG.0000000000000528DOI Listing

Publication Analysis

Top Keywords

mycobacterium bovis
4
bovis enterocolitis
4
enterocolitis immunocompromised
4
immunocompromised host
4
mycobacterium
1
enterocolitis
1
immunocompromised
1
host
1

Similar Publications

Value of anatomopathological examination in goats with a positive comparative intradermal tuberculin test as part of a tuberculosis control programme.

Vet Rec

January 2025

Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia, Murcia, Spain.

Background: Caprine tuberculosis is a chronic infectious disease caused by Mycobacterium bovis and Mycobacterium caprae. A tuberculosis control programme has been implemented using the comparative intradermal tuberculin (CIT) test. However, infection with Corynebacterium pseudotuberculsis and infection with or vaccination against Mycobacterium avium subspecies paratuberculosis (MAP) may have a negative impact on specificity.

View Article and Find Full Text PDF

Novel target and cofactor repertoire for the transcriptional regulator JTY_0672 from BCG.

Front Microbiol

January 2025

Weifang Key Laboratory of Respiratory Tract Pathogens and Drug Therapy, School of Life Sciences and Technology, Shandong Second Medical University, Weifang, China.

(Mtb) is the pathogenic agent of tuberculosis (TB). Intracellular survival plays a central role in the pathogenesis of Mtb in a manner that is dependent on an array of transcriptional regulators for Mtb. However, the functionality of JTY_0672, a member of the TetR family of transcriptional regulators, remains unknown.

View Article and Find Full Text PDF

Bacillus Calmette-Guerin (BCG) infections following intravesical BCG immunotherapy: a systematic review protocol.

Syst Rev

January 2025

Department of Medicine, Division of Infectious Diseases, Duke University, 148 Hanes House, 315 Trent Dr, Durham, NC, 27710, USA.

Background: Although intravesical Bacillus Calmette-Guerin (BCG) immunotherapy usually exhibits a favorable safety profile, it can lead to the development of BCG infections, both localized and disseminated. Understanding of BCG infections following intravesical BCG immunotherapy is limited because of the lack of consensus definitions of BCG infections and limited post-instillation follow-up. We aim to perform a systematic review of the literature of BCG infections following intravesical BCG immunotherapy to elucidate the epidemiology, risk factors, and outcomes of BCG infections.

View Article and Find Full Text PDF

STAT1 is a cytoplasmic transcription factor associated with cell growth regulation, differentiation, proliferation, metabolism, and apoptosis. IFN-mediated JAK/STAT signaling pathway is involved in eliminating intracellular pathogens and viruses. However, pathogenic variants in STAT1 can result in impaired or increased function.

View Article and Find Full Text PDF

Background: India has the highest global burden of human tuberculosis (TB) and the largest cattle herd with endemic bovine TB (bTB). However, the extent of cross-species transmission and the zoonotic spillover risk, including drug-resistant complex (MTBC) strains circulating in cattle, remain uncharacterized.

Methods: To address this major knowledge gap, we investigated tissue samples from 500 apparently healthy cattle at a slaughterhouse in Chennai, India.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!