The individual variance in the efficiency of repair of damage induced by genotoxic therapies may be an important factor in the assessment of eligibility for different anticancer treatments, the outcomes of various treatments and the therapy-associated complications, including acute and delayed toxicity and acquired drug resistance. The second part of this paper analyses the currently available information about the possibilities of using experimentally obtained knowledge about individual repair capacity for the purposes of personalised medicine and healthcare.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433894PMC
http://dx.doi.org/10.1080/13102818.2014.902532DOI Listing

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