Hepatocellular adenoma is an uncommon neoplasm, especially in the childhood age group. We describe a previously obese 13-year-old male with a giant hepatocellular adenoma requiring an extensive hepatic resection. The related pediatric tumor literature, diagnosis and clinical management is discussed.
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Gastro Hep Adv
October 2024
Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai South Nassau, One Healthy Way, Oceanside, New York.
Background And Aims: Colorectal cancer is the third most common cancer in the United States, with colonoscopy being the preferred screening method. Up to 25% of colonoscopies are associated with poor preparation which leads to prolonged procedure time, repeat colonoscopies, and decreased adenoma detection. Artificial intelligence (AI) is being increasingly used in medicine, assessing medical school exam questions, and writing medical reports.
View Article and Find Full Text PDFClin Exp Hepatol
March 2024
Department of Radiology and Diagnostic Imaging, Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Lodz, Poland.
Aim Of The Study: Hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH) are benign liver tumors. Hepatocellular adenoma has potential for growth, metaplasia and rupture; therefore, it should be monitored long term. In the current guidelines biopsy is not recommended in the standard diagnostic protocol.
View Article and Find Full Text PDFJ Physiol Sci
January 2025
Department of Pharmaceutical Physiology, Faculty of Pharmaceutical Sciences, University of Toyama, 930-0194, Toyama, Japan.
Cardiac glycosides, known as inhibitors of Na,K-ATPase, have anti-cancer effects such as suppression of cancer cell proliferation and induction of cancer cell death. Here, we examined the signaling pathway elicited by cardiac glycosides in the human hepatocellular carcinoma HepG2 cells and human epidermoid carcinoma KB cells. Three kinds of cardiac glycosides (ouabain, oleandrin, and digoxin) inhibited the cancer cell proliferation and decreased the expression level of thyroid adenoma-associated protein (THADA).
View Article and Find Full Text PDFGland Surg
December 2024
Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
Background: A right adrenal gland may present in the form of adreno-hepatic fusion (AHF), in which the adrenal cells are interspersed among the hepatocytes without septation. This rare, naturally-occurring phenomenon may be associated with preoperative misdiagnosis. We present two cases of adrenal tumor in patients with AHF that were misdiagnosed, despite thorough preoperative work-ups.
View Article and Find Full Text PDFObstet Gynecol Surv
December 2024
Assistant Professor, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN.
Importance: With a strong association between hepatic adenomas and estrogen established, understanding the risks, evaluation, and perinatal management of hepatic adenomas is necessary for obstetric clinicians.
Objective: The aim of this study is to review the preconception counseling, perinatal management, and postpartum care of hepatic adenomas.
Evidence Acquisition: A literature review identified relevant research, review articles, textbook chapters, databases, and societal guidelines.
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