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http://dx.doi.org/10.1111/ddg.12735 | DOI Listing |
EBioMedicine
October 2023
Paediatric Hematology and Oncology, University Children's Hospital Tübingen, Tübingen, Germany. Electronic address:
Background: Genomic characterisation has led to an improved understanding of adult melanoma. However, the aetiology of melanoma in children is still unclear and identifying the correct diagnosis and therapeutic strategies remains challenging.
Methods: Exome sequencing of matched tumour-normal pairs from 26 paediatric patients was performed to study the mutational spectrum of melanomas.
J Dtsch Dermatol Ges
June 2015
Department of Dermatology, Venereology, and Allergology, Würzburg University Hospital.
While neonatal skin physiology has been thoroughly examined using non-invasive techniques in recent years, only few systematic studies and review articles addressing the histopathology of neonatal skin have been published thus far. In most cases, histopathological findings of dermatoses in neonatal skin do not significantly differ from those seen in adult skin. Nevertheless, a comprehensive knowledge of embryonic and fetal skin development as well as the microanatomical structure of neonatal skin can contribute to a better understanding of various dermatoses of infancy.
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