[High central pulse pressure level is associated with cardiovascular disease in patients receiving maintenance peritoneal dialysis].

Nan Fang Yi Ke Da Xue Xue Bao

Department of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.E-mail:

Published: May 2015

AI Article Synopsis

  • The study aimed to assess the link between central pulse pressure levels and cardiovascular diseases (CVD) in patients undergoing maintenance peritoneal dialysis.
  • Data was collected from 234 patients, measuring central pulse pressure with a SphygmoCor analyzer and defining CVD through various diagnoses like heart disease and stroke.
  • Results indicated that patients with CVD had significantly higher central pulse pressure levels compared to those without, suggesting that elevated central pulse pressure could be a risk factor for CVD in this patient group.

Article Abstract

Objective: To evaluate the association between central pulse pressure level and cardiovascular diseases (CVD) in patients receiving maintenance peritoneal dialysis.

Methods: This cross-sectional study was conducted in 234 patients on maintenance peritoneal dialysis. Central pulse pressure levels were measured using a SphygmoCor analyzer, and cardiovascular diseases were defined as diagnosed ischemic heart disease, heart failure, stroke or peripheral vascular disease.

Results: The central pulse pressure levels of patients with CVD were significantly higher than those without CVD (51.7 ± 22.5 vs 43.7 ± 17.8 mmHg, P=0.004), while the brachial pulse pressure levels were comparable between the two patient groups. After adjusting for brachial pulse pressure and other relevant risk factors, central pulse pressure level was found to independently associate with CVD (adjusted OR=1.33, 95% CI 1.01-1.73, P=0.04 ).

Conclusion: High central pulse pressure level may serve as a risk factor for CVD in patients on maintenance peritoneal dialysis.

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