Purpose: To describe an unusual case of endogenous Klebsiella endophthalmitis associated with prostatic abscess in an immunocompetent patient.
Case Report: A 59-year-old previously healthy man presented with rapidly progressive retinal vasculitis in the left eye. He received an empirical antibiotic and antiviral agent intravenously followed by oral prednisolone until the etiology was identified; however, intraocular inflammation in the left eye continued to worsen, followed by the development of subretinal abscess in the contralateral eye. Finally, a diagnosis of endogenous Klebsiella endophthalmitis associated with prostatic abscess was made through a culture of the vitreous acquired by diagnostic vitrectomy. However, we could not save the vision of the left eye despite the intensive treatment with intravenous and intravitreal injections of antibiotics.
Conclusions: Rapidly progressive retinal vasculitis could be an initial sign of endogenous Klebsiella endophthalmitis even in an immunocompetent patient.
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http://dx.doi.org/10.1097/OPX.0000000000000617 | DOI Listing |
Introduction: Infectious endophthalmitis, a vision-threatening disease caused by exogenous or endogenous microbial invasion, may require vitrectomy with or without silicone oil (SO) tamponade in severe cases. SO antimicrobial effects have been suggested but not demonstrated in an in vitro environment mimicking real clinical conditions. Using an in vitro intraocular tamponade model, we investigated the antimicrobial activity of SO against 11 bacterial and 1 fungal species, including antibiotic-resistant strains of Staphylococcus aureus and Klebsiella pneumoniae.
View Article and Find Full Text PDFIndian J Nephrol
September 2024
Department of Nephrology, NU Hospitals, Bangalore, India.
Blood stream infections (BSI) are common in patients with kidney disease. Metastatic foci of infections are one of the known complications of BSI. Endophthalmitis which is defined as infection and inflammation of the inner coats of the eye ball and intraocular fluids (aqueous and vitreous), is one such focus.
View Article and Find Full Text PDFEur J Case Rep Intern Med
October 2024
Internal Medicine Department, Rashid Hospital, Dubai Health, Dubai, United Arab Emirates.
IDCases
October 2024
Department of Emergency Intensive Care Unit, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Cureus
August 2024
Department of Internal Medicine, University of Arizona College of Medicine - Tucson, Tucson, USA.
endophthalmitis is a rare cause of endogenous endophthalmitis, with very few cases documented in the US. We present a male patient in his 60s with a history of latent tuberculosis who presented to the hospital with complaints of acute bilateral vision loss that began three days prior to admission. The workup revealed bacteremia, a large hepatic abscess, severe orbital swelling, and acute angle-closure glaucoma.
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