Purpose: To evaluate the effect of simvastatin on relapse of tooth movement in rats using microtomography (micro CT), as well as the correlation of bone density with the orthodontic relapse.
Methods: Twenty-five adult male Wistar rats, divided into two groups, had stainless steel springs installed on left maxillary first molar. The molars were moved for 18 days, and after removing the springs, were applied by oral gavage, 5mg/kg of simvastatin in the experimental group for 20 days. Tooth relapse was assessed with a micro CT scanner, and the images chosen through the Data Viewer software 1.5.0.0 had their measurement guides made and checked by the software Image ProR plus 5.1, and compared by Mann-Whitney test. After rats were sacrificed, bone mineral density was evaluated by micro CT through the software CT Analyzer 1.13 and compared by independent T-test, as well as by Spearman correlation test.
Results: Relapse and bone mineral density (BMD) was lower in the experimental group than in the control group, however without a statistically significant difference.
Conclusion: Simvastatin did not inhibit the relapse of tooth movement in rats, and there was no correlation between bone density and orthodontic relapse.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/S0102-865020150050000003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical evaluation of single bond universal adhesive in non-carious cervical lesions: a 36-month retrospective study.
Clin Oral Investig
December 2024
Faculty of Dentistry, Department of Restorative Dentistry, Eskisehir Osmangazi University, Eskisehir, Turkey.
Objective: To evaluate the 36-month clinical performance of Single Bond Universal Adhesive (SBU; 3M ESPE, Germany) in non-carious cervical lesions (NCCLs) using different modes of adhesion according to the FDI criteria. The primary outcome was the retention loss of the restorations, while the secondary outcomes included marginal staining, marginal adaptation, post-operative sensitivity and tooth vitality, recurrence of caries erosion and abfraction, and tooth integrity, all evaluated according to the FDI criteria.
Materials And Methods: In this study, the SBU Adhesive was applied to 246 NCCLs of 25 patients using different modes of adhesion: Self-etch (SE), selective-enamel-etching (SLE), and etch-and-rinse (ER).
Rotations of teeth-a systematic review.
Front Oral Health
December 2024
Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Background: Rotations are frequently evaluated through various assessment methods of crowding and arch dimension, with relatively few studies discussing the extent or direction of rotations and even fewer addressing the reliability of such assessments. This systematic review aims to comprehensively analyze existing classification systems for rotated teeth and assess rotation in anterior and posterior teeth, its clinical applicability, and its impact on retention and relapse.
Search Methods: Two investigators conducted a comprehensive search in six databases, namely, PubMed, Scopus, Ovid, LILACS, Web of Science, and Cochrane CENTRAL, up to 28 March 2024.
Odontogenic keratocyst management using guided tissue regeneration: Literature review - Two case reports.
Clin Adv Periodontics
December 2024
Graduate Periodontics Program, Division of Graduate Studies, University of Detroit Mercy School of Dentistry, Detroit, Michigan, USA.
Background: Odontogenic cysts of the jaws are pathologies that require timely recognition and management. The initial diagnosis is based on clinical and radiographic appearance and dental history. A variety of surgical treatments are used for odontogenic keratocyst (OKC) depending on the clinical and radiographic presentation.
View Article and Find Full Text PDFPurpose: To help fill the knowledge gaps regarding the long-term effectiveness of peri-implantitis therapy, this retrospective study of soldiers with treated severe periodontitis (stage III gen. / IV) who had been undergoing adherent SPT for at least 20 years aimed to determine the frequency of peri-implantitis and patient-related risk factors for this, as well as the 10-year survival rates of dental implants under peri-implantitis therapy.
Materials And Methods: The observation period was between 1993 and 2023.
Potential of Japanese Macaques for Understanding Etiology and Seasonality of Repetitive Linear Enamel Hypoplasia in Nonhuman Primates.
Am J Primatol
January 2025
Oral Anatomy, School of Dentistry, Aichi Gakuin University, Nagoya, Aichi, Japan.
Japanese macaques are ideal to advance understanding of a wide-spread pattern of recurrent developmental distress in great apes, preserved as repetitive linear enamel hypoplasia (rLEH). Not only are they numerous, unendangered, and well-studied, but they are distributed from warm-temperate evergreen habitats in southern Japan to cool-temperate habitats in the north, where they are adapted behaviorally and phenotypically to winter cold and seasonal undernutrition. We provide a pilot study to determine if enamel hypoplasia exists in Japanese macaques from the north and, if temporal patterns of enamel hypoplasia are consistent with seasonal cold, undernutrition and/or exposure to secondary plant compounds.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!