Hypoestes triflora is frequently used in Rwandese native medicine to treat hepatic diseases. Premedication with a water extract of the leaves prevented the prolongation of the barbiturate sleeping time associated with carbon tetrachloride-induced liver damage in mice. The compound responsible for this protective activity was benzoic acid. Mice previously treated with benzoic acid also showed a significant diminution of the increased GOT and GPT levels seen after carbon tetrachloride administration.
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Traditional phytotherapy remedies used in Southern Rwanda for the treatment of liver diseases.
J Ethnopharmacol
November 2011
Université Libre de Bruxelles (ULB), Laboratory of Pharmacognosy, Bromatology and Human Nutrition, CP 205-9, B-1050 Brussels, Belgium.
Ethnopharmacological Relevance: Liver diseases represent a major health problem due to their complications and limited treatment possibilities. In Rwanda, given low accessibility to modern treatments, most people still rely on traditional medicinal plants. The symptomatology of many hepatic troubles (icterus) is evident for traditional healers who have a high probability of selecting efficient herbal medicines.
View Article and Find Full Text PDFThe hepatoprotective principle of Hypoestes triflora leaves.
J Ethnopharmacol
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Centre Universitaire de Recherche sur la Pharmacopée et la Médecine Traditionnelle, Faculté des Sciences, Université Nationale du Rwanda, France.
Hypoestes triflora is frequently used in Rwandese native medicine to treat hepatic diseases. Premedication with a water extract of the leaves prevented the prolongation of the barbiturate sleeping time associated with carbon tetrachloride-induced liver damage in mice. The compound responsible for this protective activity was benzoic acid.
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